Jeffrey N. Siegelman, MD
Key Points
• The timing of wound closure is determined by balancing
the risk of infection with the likelihood of scarring.
• Identify and remove foreign bodies before wound closure.
INDICATIONS
Any wound deeper than a superficial abrasion should be
considered for closure to improve the cosmetic result, preserve viable tissue, and restore tensile strength. This can be
accomplished with sutures, tissue adhesive, or staples.
Tissue adhesive may be indicated for hemostatic wounds in
low tension areas that are at low risk for infection. Staples
are appropriate for relatively linear lacerations located on
the extremities, trunk, or scalp.
CONTRAINDICATIONS
The decision about whether and when to repair a laceration is based on many factors, which can be divided
broadly into host and wound factors. Host factors include
age (elderly patients have 3-4 times higher rate of infection
and slower wound healing), malnutrition, and immunocomprornise ( eg, diabetes mellitus). Wound factors include
timing, location, mechanism, and contamination. Bacterial
counts begin to increase 3-6 hours post-injury, and every
attempt is made to achieve primary wound closure as
expeditiously as possible. However, there is no evidencedbased definitive time by which wounds must be closed.
Wounds of the face and scalp rarely become infected
( 1-2%) because the face and scalp have an excellent blood
supply; such wounds may be closed safely 24 hours or
more after injury. Infection rates of upper ( 4o/o) and lower
(7%) extremity wounds are higher, and many practitioners
20
• Evert wound edges for better aesthetic outcomes.
• Wound irrigation and debridement prevent wound
infections.
use 6-12 hours as a guideline for closing these wounds.
Lacerations sustained by a blunt, crushing force produce
more local tissue damage and therefore have a higher rate
of infection than lacerations caused by a sharp instrument
(ie, knife). A puncture wound also has a high rate of infection because bacteria are driven into the tissue and are
difficult to remove. Visible contamination within a wound
doubles the likelihood of infection. Bite wounds ( eg, dog,
cat, human) have a very high rate of infection owing to
bacterial colonization within the mouth. Generally, bite
wounds are not closed primarily unless the wound is gaping or in a cosmetically sensitive area (eg, face).
Staples and tissue adhesive should not be used on deep
wounds that would require multiple layered closure. Tissue
adhesives should not be used near mucosal surfaces, within
the scalp, or over joints (without immobilization), and care
must be taken when used near the eyes.
EQUIPMENT
When preparing the wound for closure, the following are
needed: povidone-iodine solution, local anesthetic ( 1 o/o
lidocaine with or without 1:100,000 epinephrine), 25- or
27-gauge needle, and a syringe. Irrigation is typically performed with normal saline or sterile water, a 60-mL
syringe, and an irrigation shield or 18-gauge angiocatheter;
however, some authors have argued that tap water is s uffi.
cient for uncomplicated wounds. Similarly, sterile gloves
are typically used, although one study did not show
LACERATION REPAIR
Figure 6-1. Suture instruments. From left to right:
need le driver, tissue forceps (pick-ups), and scissors.
a decreased infection rate when sterile gloves were used
compared with clean gloves in the repair of clean wounds
less than 6 hours old. Instruments needed include a needle
driver, tissue forceps (pick-ups), and scissors (Figure 6-1).
Use the smallest monofilament suture available that will
adequately appose the ends of the laceration, because thinner suture causes less scarring. Usually 4-0 (largest, for
torso and extremities) to 6-0 (smallest, for face) will suffice. Antibacterial ointment, gauze, and tape are needed for
aftercare.
PROCEDURE
� Timing
Wound healing occurs by primary, secondary, or tertiary
intention. Primary intention is the most common method
of repair and involves the approximation of wound edges
soon after the injury with the use of sutures, staples, tape, or
tissue adhesive. In secondary intention, the wound is
cleaned but left open and allowed to heal spontaneously.
This method is used when the risk of infection after primary
closure is high. Tertiary intention (delayed primary closure)
decreases infection rate in highly contaminated wounds. It is
performed by cleaning and debriding contaminated wounds
acutely, then suturing the wound after 3-5 days.
� Wound Preparation
First, ensure adequate lighting and hemostasis to allow for
a complete evaluation. A thorough neurovascular examination is required for all wounds before administration of
local anesthesia. Tendon function must also be assessed,
when appropriate. Wound exploration may detect foreign
bodies and diagnose injuries to deeper structures. If the
depth of the wound is not easily appreciated and a foreign
body is suspected (ie, patient fell on broken glass), then a
plain radiograph is recommended. Glass fragments >2 mm
are almost universally visualized on plain radiographs.
Plastic and wood foreign bodies are not radiopaque and
may require further imaging (computed tomography scan,
ultrasound, or magnetic resonance imaging).
Lacerations through hair-covered surfaces require further preparation before proceeding with repair. Clipping
hair to 1-2 mm (but not shaving) or applying antibacterial
ointment to part hair away from wound edges will allow
better visualization during wound closure and decrease
risk of infection. Do not remove hair from eyebrows or the
hairline, as this can lead to impaired or abnormal regrowth.
The edges of the wound are prepped with povidoneiodine solution. Care should be taken not to get the solution
in the wound itself, as this inhibits healing. Draw up 1 o/o
lidocaine into a syringe and prepare to infiltrate using a 25-
or 27-gauge needle. Pain of injection can be reduced by
buffering the lidocaine with bicarbonate. To do this, mix
1 mL of sodium bicarbonate with 9 mL of 1 o/o lidocaine; this
solution must be used promptly. Lidocaine is infiltrated
within the wound edges and around the entire wound (field
block). In contaminated wounds, puncture the skin around
the laceration (theoretical lower risk of infection); in clean
wounds, puncture the wound edge within the wound itself
(decreases pain of injection). Remember, the maximum
dose of lidocaine without epinephrine is 4 mg!kg. This
equates to 280 mg in a 70-kg (154 lb) man or 28 mL of
1 o/o lidocaine ( 10 mgfmL). Lidocaine with epinephrine has a
maximum dose of 7 mg!kg. Other advantages of adding
epinephrine include decreased bleeding and increased dura
tion of anesthetic. Traditional teaching dictates that caution
should be used with epinephrine in end-arterial fields (eg,
fingers, toes) for patients with vascular injury or a history of
vascular disease; however, little evidence exists supporting
this practice.
Wound irrigation and debridement of devitalized tissues are the two most important ways to decrease the
incidence of wound infection. When irrigating a wound,
use a commercially available shield to avoid accidental
exposure to the health care worker and create the required
pressure to decrease bacterial counts. If unavailable, an
1 8-gauge angiocatheter with a 60-mL syringe can be used.
Irrigation with a saline bag or bottle with holes punched
into the top does not create enough pressure to adequately
reduce bacterial counts. The amount of saline required to
irrigate a wound is not known, but a basic guideline is to
use 50-100 mL for each 1 em of laceration.
� Wound Closure
A few principles should be considered when placing simple
interrupted sutures (Figure 6-2). Clamp the needle driver
CHAPTER 6
---- -
Figure 6-2. Simple interru pted suture.
in the middle of the needle. Grasping the end of the
needle will damage the cutting edge and make suturing
more difficult. Insert the needle at 90 degrees to help
evert the tissue. Eversion permits more rapid epithelialization than inversion and avoids a scar that is depressed
after contraction. The tissue forceps are used to lift up the
skin on one side of the laceration. Grasping the tissue too
tightly (especially when using forceps with teeth) may
damage the tissue and should be avoided. Instead use the
teeth or a skin hook to lift the subcutaneous tissues.
When the needle is inserted, maintain the same depth as
the other side. Use 4-5 instrument ties to secure the knot.
Avoid pulling the wound edges too tightly (indicated by
blanching) because this may strangulate the wound
edges, reducing blood supply. Begin in the middle of the
wound, and then bisect the resulting segments with s ubsequent sutures until the wound is sufficiently approximated. As a rule, the distance from the needle insertion to
the wound edge should be the same on both sides, as well
as the same depth. The distance between stitches should
also be equal. On the face, this will be 1-3 mm and can be
farther apart elsewhere.
.
Vertical and horizontal mattress sutures both provtde excellent wound eversion and help to better
approximate wound edges that are under tension and
difficult to pull together (Figures 6-3 and 6-4). Vertical
mattress sutures are especially useful in lacerations in
which there is minimal subcutaneous tissue for deep
sutures such as the hands or over joints. In addition,
these sutures will help stop bleeding from a scalp laceration. The disadvantage of these sutures is that they may
strangulate the tissues.
Figure 6-3. Vertical mattress.
Deep sutures are indicated in wounds with multiple
layers of tissue to close ( eg, full thickness lip lacerations)
and to minimize tension on superficial skin for gaping
wounds. Deep sutures should be placed with absorbable
suture material. To get the knot to the depth of the wound,
make the first pass of the needle from the deep portion of
the wound to the superficial portion (Figure 6-5 ). Avoid
infection by placing only enough deep sutures to effectively
bring the wound edges together and cut the suture as close
to the knot as possible.
Staples are placed by first everting the edges of the
wound and then firing the automatic stapler with the same
principles of spacing as above.
Tissue adhesive is applied using 4-5 layers on a hemostatic, cleaned, dry wound, which the provider approximates while applying the adhesive. Avoid getting the
adhesive into the wound itself. Wound tape may be applied
to the wound before placing the adhesive to provide
improved approximation.
\
\
\�
.A. Figure 6-4. Horizonta l mattress.
\
\
\
LACERATION REPAIR
Figure 6-5. Deep dermal stitch. On the first pass,
the needle enters at the depth of the wou nd so that
the knot wi ll end up at the bottom of the wound.
..... Wound Aftercare
Topical antibiotic ointments provide a moist environment
that assists epithelization and reduces the rate of infection.
They should not be used after the use of tissue adhesive.
Prophylactic oral antibiotics are r ecommended for heavily
contaminated wounds, significant animal or human bites,
areas prone to infection (mouth, plantar aspect of the
foot), open fractures, tendon or joint involvement, immunocompromised patients, a prosthetic heart valve, or deep
puncture wounds.
In patients with full childhood immunizations, tetanus
toxoid, given with diphtheria toxoid (Td 0.5 mL administered intramuscularly [IM) ), is administered after a minor,
clean wound if the last booster was > 10 years ago. In all
other wounds (contaminated, puncture, crush), tetanus
toxoid is given if the last booster was >5 years ago. Tetanus
immune globulin (TIG) 3,000-5,000U IM and around the
wound is administered to patients with a history of <3
immunizations and a contaminated wound.
Apply a topical ointment ( eg, bacitracin) and then a
sterile dressing. The dressing may be removed in 24 hours
and the wound can be gendy cleansed with soap and water,
using caution to blot the sutures dry.
Suture removal is recommended in 3-5 days for face
and neck; 7-10 days for upper extremity, chest, legs, and
scalp; and 10-14 days for hand, back, buttocks, foot, and
overlying joints.
COMPLICATIONS
Complications may include infection and scarring. Despite
all efforts to reduce the risk of infection, this complication
can still occur. The patient should be instructed to return
at the first signs of infection (ie, fever, purulent drainage,
or erythema). Patients with high-risk wounds should be
asked to return to their physician or the emergency department within 24-48 hours to have the wound reexamined
by a physician. Patients should also be instructed that a
scar will form with healing. Scarring is more significant
after deeper wounds, or those that do not run parallel to
natural skin lines, and when absorbable sutures are used.
There are insufficient data to recommend routine use of
topical healing creams such as vitamin E, aloe vera, or
other commercially available products.
SUGGESTED READING
Desai S, Stone SC, Carter WA. Wound preparation. In:
Tintinalli JE, Stapczynski JS, Ma OJ, Clince DM, Cydulka,
RK, Meckler GD. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, NY: McGraw-Hill, 20 1 1,
pp. 301-306.
Singer AJ, Hollander JE. Methods for wound closure. In:
Tintinalli )E, Stapczynski JS, Ma OJ, Clince DM, Cydulka, RK,
Meckler GD. Tintinalli's Emergency Medicine: A Comprehensive
Study Guide. 7th ed. New York, NY: McGraw-Hill, 20 1 1,
pp. 306-3 15.
Singer AJ, Hollander JE, Quinn JV. Evaluation and management
of traumatic lacerations. N Eng! J Med. 1997;337:1 142-1 148.
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