Principe actif
Prednisolone
SOLUPRED est habituellement prescrit pour :
Lupus érythémateux disséminé
Vascularite systémique
Polymyosite
Sarcoïdose viscérale
Dermatose bulleuse auto-immune
Angiome du nourrisson
Lichen plan
Urticaire aiguë
Dermatose neutrophilique
Rectocolite hémorragique
Maladie de Crohn
Hépatite chronique active auto-immune
Hépatite alcoolique aiguë sévère
Thyroïdite subaiguë de De Quervain sévère
Hypercalcémie
Purpura thrombopénique immunologique sévère
Anémie hémolytique auto-immune
Hémopathie maligne lymphoïde
Erythroblastopénie chronique acquise
Erythroblastopénie chronique congénitale
Péricardite tuberculeuse
Tuberculose mettant en jeu le pronostic vital
Pneumopathie à Pneumocystis carinii avec hypoxie sévère
Traitement antiémétique au cours des chimiothérapies antinéoplasiques
Poussée oedémateuse et inflammatoire associée au traitement antinéoplasique
Syndrome néphrotique à lésions glomérulaires minimes
Syndrome néphrotique des hyalinoses segmentaires et focales primitives
Néphropathie lupique
Sarcoïdose granulomateuse intrarénale
Vascularite avec atteinte rénale
Glomérulonéphrite extracapillaire primitive
Myasthénie
Oedème cérébral tumoral
Chronic polyradiculoneuritis
West syndrome
Lennox-Gastaut syndrome
Relapsed multiple sclerosis
Anterior uveitis
Posterior uveitis
Edematous proptosis
Optic neuropathy
Serous otitis
Nasosinus polyposis
Acute sinusitis
Chronic sinusitis
Seasonal allergic rhinitis
Subglottic laryngitis
Persistent asthma
Severe acute asthma
Chronic obstructive pulmonary disease
Active sarcoidosis
Diffuse interstitial pulmonary fibrosis
Rheumatoid arthritis
Polyarthritis
Polymyalgia rheumatica
Horton's disease
Acute articular rhumatism
Cervico brachial neuralgia
transplant rejection
Graft versus host reaction
Indications SOLUPRED-
CONDITIONS OR DISEASES
COLLAGENOSES-CONNECTIVITIES
Progressive outbreaks of systemic diseases, including: systemic lupus erythematosus, vasculitis, polymyositis, visceral sarcoidosis.
DERMATOLOGICAL
severe autoimmune bullous dermatoses, in particular pemphigus and bullous pemphigoid,
forms of infant angiomas,
certain forms of lichen planus,
certain acute urticaria,
severe forms of neutrophilic dermatoses.
DIGESTIVES
progressive flare-ups of ulcerative colitis and Crohn's disease,
autoimmune chronic active hepatitis (with or without cirrhosis),
Severe acute alcoholic hepatitis, histologically proven.
ENDOCRINE
severe De Quervain's subacute thyroiditis,
certain hypercalcaemias.
HEMATOLOGICAL
severe immunological thrombocytopenic purpuras,
autoimmune hemolytic anemias,
in combination with various chemotherapies in the treatment of lymphoid malignancies,
chronic acquired or congenital erythroblastopenia.
INFECTIOUS
tuberculous pericarditis and serious forms of tuberculosis involving the vital prognosis,
Pneumocystis carinii pneumonia with severe hypoxia.
NEOPLASTIC
antiemetic treatment during antineoplastic chemotherapy,
edematous and inflammatory flare-up associated with antineoplastic treatments (radio and chemotherapy).
· NEPHROLOGICAL
nephrotic syndrome with minimal glomerular lesions,
o nephrotic syndrome of segmental and focal primitive hyalinosis,
o stage III and IV of lupus nephropathy,
intrarenal granulomatous sarcoidosis,
vasculitis with renal involvement,
primary extra-capillary glomerulonephritis.
NEUROLOGICAL
myasthenia,
cerebral edema of tumoral cause,
chronic, idiopathic, inflammatory polyradiculoneuritis,
infantile spasm (West syndrome) / Lennox-Gastaut syndrome,
relapsed multiple sclerosis, following intravenous corticosteroid therapy.
OPHTHALMOLOGICAL
or severe anterior and posterior uveitis,
edematous proptosis,
certain optic neuropathies, following intravenous corticosteroid therapy (in this indication, the first-line oral route is not recommended).
certain serous otitis,
nasal polyposis,
certain acute or chronic sinusitis,
seasonal allergic rhinitis in short cure,
acute stridulous laryngitis (subglottic laryngitis) in children.
RESPIRATORY
persistent asthma preferably in short cure in case of failure of inhaled treatment at high doses,
exacerbations of asthma, in particular severe acute asthma,
chronic obstructive pulmonary disease in evaluation of the reversibility of the obstructive syndrome,
progressive sarcoidosis,
diffuse interstitial pulmonary fibrosis.
· RHEUMATOLOGY
rheumatoid arthritis and certain polyarthritis,
polymyalgia rheumatica and Horton's disease,
severe and rebellious cervico-brachial neuralgia.
TRANSPLANTATION OF ORGANS AND ALLOGENIC HEMATOPOIETIC STEM CELLS
prophylaxis or treatment of transplant rejection,
prophylaxis or treatment of graft versus host disease.