Abstract
OBJECTIVE: To analyze populational trends and perioperative complications following conservative surgery versus oophorectomy in women <50
DESIGN: Population-based retrospective observational study.
SETTING: Nationwide Inpatient Sample in the United States (2001-2015).
POPULATION: 89,177 ovarian torsions including 20,597 (23.1%) conservative surgeries and 68,580 (76.9%) oophorectomies.
METHODS: (i) trend analysis to assess utilization of conservative surgery over time, (ii) multivariable binary logistic regression to identify independent factors associated with conservative surgery, and (iii) inverse probability of treatment weighting with a generalized estimating equation to analyze perioperative complications.
MAIN OUTCOME MEASURES: trends, characteristics, and complications related to conservative surgery.
RESULTS: Performance of conservative surgery increased from 18.9% to 25.1% between 2001-2015 (32.8% relative increase, P=0.001) but decreased steadily after age 15 and sharply declined after age 35 (P<0.001).<0.001).<0.001)
CONCLUSION: There was an increasing utilization of conservative surgery for ovarian torsion in the United States in recent years. Our study suggests that conservative surgery for ovarian torsion may not be associated with increased perioperative complications.
PMID: 32086987 [PubMed - as supplied by publisher]
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pubmed: caandvteortroorpul
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24 February 2020
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Cancer & Heart (Cardio-Oncology, Cardiotoxicity, TEV)
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Trastuzumab-Related Cardiotoxicity and Cardiac Care in Patients With HER2 Positive Metastatic Breast Cancer.
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