Nonbacterial thrombotic endocarditis is a form of a thrombotic angiopathy involving the endothelial lined endocardial surfaces of the heart
Abstract
Nonbacterial thrombotic endocarditis is a form of a thrombotic angiopathy involving the endothelial lined endocardial surfaces of the heart which includes valves and the chamber walls. Underlying etiologies for nonbacterial thrombotic endocarditis include autoimmune diseases, hypercoagulable states, in the setting of certain malignant neoplasms, and physical injury. The pathogenesis for these processes is that of primary endothelial injury resulting in a thrombotic angiopathy. We present a patient with heart failure being evaluated before hematopoietic stem cell transplantation who had previously been provided with chemotherapy and whose cardiac magnetic resonance imaging reveals findings suggestive of amyloidosis. A subsequent endomyocardial biopsy instead showed nonbacterial thrombotic endocarditis characterized by the endocardium with fibromyxoid thickening and overlying fresh fibrin. This case highlights histopathologic findings of chemotherapy-associated nonbacterial thrombotic endocarditis involving the right ventricle wall of the endocardium, therefore expanding the radiological differential in patients with cardiac magnetic resonance imaging findings suggestive of amyloidosis.
PMID: 32142924 [PubMed - as supplied by publisher]
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pubmed: ctoall&ca or conall
Thoracic and cardiovascular surgeries in Japan during 2017 : Annual report by the Japanese Association for Thoracic Surgery.
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Authors: Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery, Shimizu H, Okada M, Tangoku A, Doki Y, Endo S, Fukuda H, Hirata Y, Iwata H, Kobayashi J, Kumamaru H, Miyata H, Motomura N, Natsugoe S, Ozawa S, Saiki Y, Saito A, Saji H, Sato Y, Taketani T, Tanemoto K, Tatsuishi W, Toh Y, Tsukihara H, Watanabe M, Yamamoto H, Yokoi K, Okita Y
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Cancer & Heart (Cardio-Oncology, Cardiotoxicity, TEV)
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pubmed: caandvteortroorpul
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