Adolescents become more susceptible to certain diseases, as the immunity
wanes with age and they travel more often.
Recommended Vaccines for Adolescents
• Rubella-RA 27/3 is given if MMR Measles, Mumps, Rubella has not been
given at 15 months or thereafter. Arthralgia, arthritis and idiopathic
thrombocytopenic purpura may occur.
• Hepatitis-B WHO has recommended universal Hepatitis B vaccination.
For adolescents 0,1 and 6 months is a preferred schedule (no booster is
needed), if not vaccinated earlier.
• Typhoid Vi polysaccharide vaccine. It is given at 10 and 16 years of age.
Dose of 0.5 ml (25 μg) is given every 3 years, lifelong.
• Hepatitis A. Two doses are given at 6 months interval (from 1 year
onwards). If exposed, give within 10 days to the contacts.
• Chickenpox: Give to children >13 years since symtoms are more severe
in adults. Two doses are given. 4 to 8 weeks apart. After vaccination,
protection is only partial and child may develop a mild breakthrough disease.
• Human Papilloma Virus Immunization HPV Vaccine — A New Vaccine: Human
papilloma virus HPV has been linked to cancer of cervix and genital warts.
– The quadrivalent HPV vaccine (Gardasil) is given in age group of 9 to
26 years to girls ideally, prior to the onset of sexual activity.
– It protects against vulvar and vaginal cancers, as well.
– Efficacy is good and seroconversion is excellent and better than the
naturally occurring infection.
– It has purified recombinant virus-like particles of major capsid (L1)
protein of HPV.
– Mainly four types can cause cervical cancers, genital wart and
precancerous lesions. Each 0.5 ml IM dose given in the deltoid region
contains these four types:
o 20 mcg of type 6
o 40 mcg of type 11
o 40 mcg of type 16
o 20 mcg of type 18.
Dosage Schedule
• 3 doses of Gardasil are given at 0, 2 and 6 months
• 3 doses of Cervarix are given at 0, 1 and 6 months.
Side Effects
Hematoma, allergic reactions, fever, headache and gastroenteritis. Avoid the
vaccine in pregnancy.
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