Abstract
Owing to early diagnosis and rapid development of
treatments for cancers, the five-year survival rate of
all cancer types has markedly improved worldwide. Over
time, however, there has been an increase in the number
of cancer patients who develop coronary artery disease
(CAD) due to different causes. First, many risk factors
are shared between cancer and CAD. Second, inflammation
and oxidative stress are common underlying pathogeneses
in both disorders. Lastly, cancer therapy can result in
endothelial injury, coronary artery spasm, and
coagulation, thereby increasing the risk of CAD. As
more cancer patients are being diagnosed with CAD,
specialized cardiac care should be established to
minimize the cardiovascular mortality of cancer
survivors.
PMID: 32055781 [PubMed]
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pubmed: ctoall&ca or conall
Advances in Preclinical Research Models of Radiation-
Induced Cardiac Toxicity.
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