Onset Gradual Rapidly increasing Sudden Rapidly increasing
Character Gnawing Constant Constant Constant
Radiation Into back Below right scapula Into back Into genitalia and inner thigh
Associated symptoms Non-specific Non-specific Non-specific Non-specific
Special times Nocturnal and especially
Unpredictable After heavy drinking Following periods of
2 –2 hours 4–24 hours >24 hours 4–24 hours
Exacerbating factors Stress, spicy foods, alcohol,
non-steroidal antiinflammatory drugs
Relieving factors Food, antacids, vomiting – Sitting upright –
Severity Mild to moderate Severe Severe Severe
6.3 Non-alimentary causes of abdominal pain
Myocardial infarction Epigastric pain without tenderness
Angor animi (feeling of impending death)
Lateralised pain restricting movement
Tenderness overlying involved vertebra
Cord compression Pain on percussion of thoracic spine
Hyperaesthesia at affected dermatome with
Pleurisy Lateralised pain on coughing
Herpes zoster Hyperaesthesia in dermatomal distribution
Diabetic ketoacidosis Cramp-like pain
Suprapubic and iliac fossa pain, localised
Torsion of testis/ovary Lower abdominal pain
98 • The gastrointestinal system
Patients with dysphagia complain that food or drink sticks when
• onset: recent or longstanding
• nature: intermittent or progressive
• difficulty swallowing solids, liquids or both
• the level the patient feels food sticks at
• any regurgitation or reflux of food or fluid
• any associated pain (odynophagia), heartburn or
Do not confuse dysphagia with early satiety, the inability to
complete a full meal because of premature fullness, or with
globus, which is a feeling of a lump in the throat. Globus does
not interfere with swallowing and is not related to eating.
Neurological dysphagia resulting from bulbar or pseudobulbar
palsy (p. 129) is worse for liquids than solids, and may be
accompanied by choking, spluttering and fluid regurgitating
Neuromuscular dysphagia, or oesophageal dysmotility, presents
in middle age, is worse for solids and may be helped by liquids and
sitting upright. Achalasia, when the lower oesophageal sphincter
fails to relax normally, leads to progressive oesophageal dilatation
above the sphincter. Overflow of secretions and food into the
respiratory tract may then occur, especially at night when the
patient lies down, causing aspiration pneumonia. Oesophageal
dysmotility can cause oesophageal spasm and central chest
pain, which may be confused with cardiac pain.
A pharyngeal pouch may cause food to stick or be regurgitated,
and may lead to recurrent chest infections due to chronic silent
Exacerbating and relieving factors
Pain exacerbated by movement or coughing suggests
inflammation. Patients tend to lie still to avoid exacerbating the
pain. People with colic typically move around or draw their knees
up towards the chest during spasms.
Excruciating pain, poorly relieved by opioid analgesia, suggests
an ischaemic vascular event, such as bowel infarction or ruptured
abdominal aortic aneurysm. Severe pain rapidly eased by potent
analgesia is more typical of acute pancreatitis or peritonitis
secondary to a ruptured viscus.
Features of the pain can help distinguish between possible
The majority of general surgical emergencies are patients with
sudden severe abdominal pain (an ‘acute abdomen’). Patients
may be so occupied by recent and severe symptoms that they
forget important details of the history unless asked directly. Seek
additional information from family or friends if severe pain, shock
or altered consciousness makes it difficult to obtain a history
from the patient. Note any relevant past history, such as acute
perforation in a patient with known diverticular disease. Causes
range from self-limiting to severe life-threatening diseases (Box
6.4). Evaluate patients rapidly, and then resuscitate critically ill
patients immediately before undertaking further assessment
and surgical intervention. Parenteral opioid analgesia to alleviate
severe abdominal pain will help, not hinder, clinical assessment.
In patients with undiagnosed acute abdominal pain, reassess
their clinical state regularly, undertake urgent investigations
and consider surgical intervention before administering repeat
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