lead to the rapid development of a targeted differential.
nature of the pain at onset, and how the pain behaves
is sudden and severe at onset is often associated with the
rupture of a blood vessel or hollow viscus ( eg, ruptured
teral colic), or gonadal torsion. In contrast, inflammatory
conditions tend to have a more insidious onset, as is seen
with appendicitis. Pain whose progression is colicky in
nature is suggestive of peristaltic activity in the setting of
an obstructed lumen ( eg, ureteral, biliary, intestinal
The manner in which the pain radiates can suggest a
specific disease. Pain radiating to the back is often seen
with pancreatitis. Pain radiating to the right infrascapular
region is associated with biliary tract disorders. Pain that
radiates to the groin may indicate a ruptured aortic aneurysm or nephrolithiasis.
Associated symptoms involving the gastrointestinal,
genitourinary, and cardiopulmonary systems should be
disease processes. Nausea and vomiting are nonspecific
symptoms, although it is worthwhile noting the temporal
relationship between them. Surgical causes of abdominal
pain classically present with pain preceding vomiting,
whereas the reverse is often seen with medical etiologies.
they can also be caused by appendicitis or pelvic abscess.
Hematuria should raise concern for nephrolithiasis or a
malignancy in the genitourinary tract. Vaginal bleeding
A thorough past medical/surgical history, medications,
allergies, and social history should also be obtained. The
existence of known coronary artery or cerebrovascular
disease should raise suspicion for vascular disease of the
abdomen. Corticosteroids and immunosuppressants
should alert the clinician that the patient may not present
with typical symptoms or exam findings. Knowledge of
anticoagulants is critical in constructing the differential
diagnosis as well as making sure reversal is not needed
before any operative intervention. Heavy alcohol use raises
the possibility of hepatitis or pancreatitis.
Vital signs should be readily noted, with tachycardia and/
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