Obtain a head computed tomography (CT), searching for
signs of hypertensive encephalopathy or intracranial hem
orrhage in patients presenting with altered mental status,
papilledema, focal neurologic deficits, or seizure. Order a
chest x-ray (CXR) to look for signs of flash pulmonary
edema or aortic dissection in patients with chest pain, back
pain, or shortness of breath. Pursue CT angiography of the
chest and abdomen in patients with suspicion of aortic
Rapidly evaluate all patients with severe hypertension for
the presence of hypertensive emergency (hypertensive
encephalopathy, intracranial hemorrhage, flash pulmonary
edema, acute coronary syndrome, aortic dissection, and
Severe hypertension (BP > 1 80/1 1 0)
History and physical exam, re-measure BP
acute kidney injury). Utilize the history and physical exam
to help narrow the differential diagnosis and obtain the
appropriate laboratory and imaging studies to both confirm
end-organ injury and guide further therapy (Figure 1 8-1
Hypertensive emergency requires immediate BP reduc
tion to limit continuing end-organ damage. The goal is
not to normalize the BP ( < 140/90 mmHg), but rather to
Table 1 8-1. Hypertensive emergency diag noses with findings.
Findings on H&P, Labs, and Imaging
AMS, headache, vomiting and papilledema; labs and a head frequently normal
Headache, coma and focal neurologic deficits; a head with hemorrhage
SOB, chest pain and inspiratory crackles on lung exam; elevated BNP; CXR with cardiomegaly
Chest pain, SOB; elevated troponin; ECG with ischemic changes
Severe chestjback pain; unequal pulses; CXR with wide mediastinum, a chest with dissection
acutely elevated BUN and creatinine
ECG, electroca rdiogram; RBCs, red blood cel ls; SOB, shortness of breath.
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