Patients with cellulitis or abscesses should be admitted if
there is an extensive area of involvement or if they are
systemically ill, have significant comorbid illness, or are
immune-compromised. All patients with necrotizing
infections should be admitted to an intensive care unit
for broad-spectrum antibiotic therapy after surgical
Patients with cellulitis or a drained abscess with limited
area of involvement, no or minimal systemic symptoms,
and no significant comorbidities may be discharged.
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Management of skin and soft-tissue infection. N Eng! l Med.
Dewitz F. Soft tissue. In: Ma OJ, Mateer JR, Blaivas M. Emergency
Ultrasound. 2nd ed. New York, NY: McGraw-Hill, 2008,
Infectious Diseases Society of America. Practice Guidelines for
the Diagnosis and Management of Skin and Soft-Tissue
Infections. http://www.idsociety.org/uploadedFiles/IDSN
Guidelines-Patient_ Care/PDF _Library I Skin o/o20and %20
Softo/o20Tissue.pdf. CID 2005:41.
Kelly EW, Magliner D. Soft tissue infections. In: Tintinalli JE,
Stapczynski JS, Ma OJ, Cline DM, Cydulka RK, Meckler GD.
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Guide. 7th ed. New York, NY: McGraw-Hill, 20 1 1,
Wang CH, Khin LW, Heng KS, Tan KC, Low CO. The
LRINEC ( Laboratory Risk Indicator for Necrotizing
• A high index of suspicion is needed fo r the initial
diagnosis of human immu nodeficiency virus (H IV),
particula rly in the context of atypical presenting
symptoms. Consider acute HIV in the patient who
presents with a mononucleosis-like i nfection, but
with negative monos pot testing.
• CD4 T-cell count is correlated with risk for opportunistic
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