71. B. A mixed venous PO2

lower than 30 mm Hg associated with metabolic acidosis

suggests inadequate tissue perfusion. Temperature correction of PaCO2 and pH is

probably not necessary. Urine output may serve as a guide to the adequacy of renal

perfusion, with an output of 0.5 to 1 mL/kg/hr, indicating adequate renal perfusion.

72. C. Monitoring of coronary sinus pressures during retrograde administration is used

to assess proper catheter placement. The anatomical location of coronary sinus ostia

makes it very difficult for proper visualization by the surgeon. A properly placed

coronary sinus catheter will have pressure of 40 to 60 mm Hg during a 200-mL/min

infusion. If the pressure at the distal tip of the coronary sinus catheter during

cardioplegia administration at 200 mL/min is equal to central venous pressure, the

catheter is not in the coronary sinus but is most likely in the right atrium or in the

superior vena cava. Being up against a wall produces a very high (>100 mm Hg)

pressure. Positioning of the coronary sinus catheter should be checked with

transesophageal echocardiography and manual feel by the surgeon. If the catheter is

too deep, cardioplegia to the right ventricle will be compromised, resulting in poor

right-ventricular protection.

73. C. At 30°C, the heart muscle consumes oxygen at a rate of 8 to 10 mL/100 g/min,

provided it is normally contracting. Oxygen consumption in the fibrillating ventricle

at 22°C is 2 mL/100 g/min. The electromechanically quiet heart at 22°C consumes

oxygen at a rate of 0.3 mL/100 g/min.

74. A. The extra volume of crystalloid used in priming the CPB circuit may produce a

sudden dilution of circulating drug concentrations. This creates a high chance of

patient recall/ movement. Supplemental anesthetics, such as benzodiazepines or

opioids, and an additional dose of nondepolarizing muscle relaxant, may be

administered prophylactically. Volatile anesthetics delivered using vaporizers

incorporated into the CPB circuit have largely negated this problem along with the

use of BIS monitors. The effect of hemodilution on drug concentrations is likely to

be offset by a decreased need for drugs during hypothermia. On the contrary,

anesthetic requirements seem to be minimal if the patient was adequately rearmed at

the conclusion of CPB. Therefore, additional anesthesia is not routinely required

during rewarming at the termination of CPB.

75. B. Low SVR is a very common hemodynamic abnormality after CPB. This makes

weaning from CPB very difficult. SVR is usually calculated using the formula mean

arterial pressure (mm Hg) − central venous pressure (mm Hg)/pump flow (L/mi) ×

80.

SVR should be between 1,200 and 1,400 prior to CPB separation. The units of

SVR are dyn s/cm5

. SVR can be normalized with a vasoconstrictor prior to weaning

from CPB. By this, we are attempting to match the vascular input impedance to the

cardiac output impedance and optimizing energy transfer.

76. D. Acute mitral regurgitation (MR) post–CPB is often noticed as a prominent V

wave in PAOP tracing. If there is a transesophageal echocardiograph (TEE) in place,

we may be able to see a wide MR jet, with observation of an echogenic mass

attached to the mitral valve or when a mobile mass is seen to prolapse into the left

atrium during systole and to move back into the left ventricle during diastole. The

posterior papillary muscle, along with the posterior wall, is entirely perfused either

by the right coronary artery (RCA) or by the third obtuse marginal branch, usually by

a single artery unlike the anterior, which derives its blood supply from two arteries. It

is usually a complication of acute mitral infarction but maybe seen at the end of CPB

due to inadequate myocardial protection (warm blood in the adjacent descending

aorta providing inadequate protection) during CPB or air entry into the RCA. Acute

MR due to volume overload from excessive fluid administration is usually a central

MR as evidenced in TEE with a distended ventricle and can be managed by

decreasing the preload.

Thoracic Anesthesia

Deppu Ushakumari and Ashish Sinha

1. Which of the following is not a characteristic feature of asthma?

A. Chronic inflammatory changes in the submucosa of the airways

B. Airway hyper responsiveness

C. Reversible expiratory airflow obstruction

D. Elastase deficiency in the airways

2. A 55-year-old male presented to you with a pulmonary function test report, which

shows an increase of FEV1 percent predicted of more than 12%, and an increase in

FEV1 of greater than 0.2 L in response to bronchodilators. Which characteristic of

his respiratory illness is depicted here?

A. Bronchial asthma—acute bronchodilator responsiveness

B. Chronic obstructive pulmonary disease (COPD)—variability in airflow

obstruction

C. COPD—acute bronchodilator responsiveness

D. All the above are correct

3. Which of the following techniques is associated with a lower complication rate

related to bronchospasm in the asthmatic population?

A. Regional anesthesia

B. General anesthesia—laryngeal mask airway (LMA)

C. General anesthesia—endotracheal tube (ETT)

D. Combined general and neuraxial anesthesia

4. A 22-year-old patient with a history of moderate persistent asthma on medium-dose

inhaled corticosteroids and long-acting inhaled β-agonist presents for an emergency

appendectomy. On clinical examination, he is actively wheezing, but maintaining an

oxygen saturation of 99% on room air. Which of the following statements about this

clinical scenario is most appropriate?

A. Presence of wheezing on physical examination indicates that he is having a

severe attack of asthma

B. Volatile anesthetics cause bronchodilation through catecholamine-independent

mechanisms

C. Increased airway resistance that occurs intraoperatively is usually due to acute

exacerbation of asthma

D. A laryngeal mask airway (LMA) is more stimulating to the airway than an

endotracheal tube, and should be avoided in asthmatics

5. During the above case, the end-tidal sevoflurane concentration reads 3.5, but the

anesthesia ventilator is alarming because of high peak airway pressures. Which of

the following is the most likely cause?

A. Acute bronchospasm

B. Anaphylactic reaction to intravenous muscle relaxant that you just administered

C. Mechanical causes of obstruction

D. Inadequate depth of anesthesia

6. At the end of the above case, the surgeon requests you to extubate the patient fully

awake because he found extensive intestinal adhesions and is afraid of retained

gastric contents in the stomach. Which of the following will be your most likely plan

of action?

A. Insert an orogastric tube, empty the stomach as much as you can, and proceed

with a deep extubation to avoid bronchospasm

B. Administer intravenous lidocaine to decrease the likelihood of airway

stimulation and wait till the patient is fully awake before extubation

C. Shut off the inhalational agent and use intravenous propofol to avoid

transitioning through a rocky stage-2 wake up

D. Transition to a laryngeal mask airway (LMA) under sevoflurane anesthesia and

let the patient wake up with an LMA

7. Which of the following is true regarding administering general anesthesia to a

chronic obstructive pulmonary disease (COPD) patient?

A. Nitrous oxide + opioid technique is ideal

B. Use large tidal volumes

C. Use lower breathing rates to permit more exhalation time

D. Correct the hypercapnia intraoperatively to help extubate early

8. Anesthetic considerations for a patient with severe pulmonary hypertension include

all the following, except

A. Right heart catheterization is the gold standard for diagnosis

B. Mortality in pregnant patients undergoing vaginal delivery is very small as

opposed to cesarean section

C. Minimize tachycardia, hypoxemia, and hypercapnia during anesthetic

management

D. Cardiac output from a failing right ventricle depends on filling pressure from

venous return and pulmonary pressure

9. Which of the following is not a part of the “STOP BANG” screening questionnaire

for obstructive sleep apnea (OSA)?

A. Snoring

B. Observed apnea

C. Exercise tolerance

D. High blood pressure

10. Risk factors associated with increased perioperative morbidity and mortality in

thoracic surgery patients include all the following, except

A. Extent of lung resection

B. Age older than 70 years

C. Experience of the operating surgeon

D. Male sex

11. The following is not necessarily a part of prethoracotomy respiratory assessment

A. Pulmonary capillary wedge pressure >18 mm Hg

B. Predicted postoperative FEV1 >40%

C. VO2 max >15 mL/kg/min

D. Predicted postoperative diffusing capacity for carbon monoxide (DLCO) >40%

12. Which of the following is one of the benefits regarding cessation of smoking 12 to 24

hours prior to surgery?

A. Shift of oxyhemoglobin dissociation curve to the right

B. Improvement in mucociliary transport

C. Decrease in sputum production

D. Improved small-airway function

13. In surgical cases requiring lung isolation

A. Measurement of tracheal width from a posteroanterior chest radiograph is of no

use in selecting the size of a double-lumen tube (DLT)

B. More frequent use of left-sided DLT is based on the anatomy of

tracheobronchial tree

C. Uniform ventilation to all lobes is most likely achieved by a right-sided DLT

because it has a ventilation slot in the bronchial tube

D. Fiber–optic confirmation of correct DLT placement is not required if you have

good clinical confirmation

14. A 59-year-old lady is intubated with a 37 left-sided double-lumen tube (DLT) for

wedge resection of left lower lobe nodule. After intubation, you inflate the bronchial

cuff and ventilate the left lung through the bronchial lumen without any difficulty.

Then you proceed to inflate the tracheal cuff and ventilate through the tracheal

lumen. You notice a very high resistance to air flow. Which of the following events

is most unlikely with the said clinical picture?

A. Left DLT too deep with the tracheal outlet into the left main-stem bronchus

B. Left DLT displaced with the bronchial cuff herniated at carina

C. Left DLT entered the right bronchus with the tracheal outlet in the right main

stem

D. DLT too far out with the bronchial lumen sitting just above the carina

15. What would you do if you have the following situation with a bronchial blocker for

left lung surgery?

Figure 12-1.

A. Appropriate positioning for this surgery

B. Withdraw the bronchial blocker a couple of centimeters

C. Insert the bronchial blocker a few centimeters farther down

D. Remove the bronchial blocker and reinsert it into the left side

16. In which of the following situations is applying continuous positive-airway pressure

(CPAP) to the nondependent lung most ideal for improving oxygenation?

A. Bronchopleural fistula

B. Open lobectomy

C. Massive pulmonary hemorrhage

D. Sleeve resection

17. Which of the following statements is false regarding ventilation/perfusion

relationship in a lateral decubitus position during spontaneous ventilation?

A. The ventilation/perfusion matching is preserved

B. Contraction of dependent hemi diaphragm is more efficient

C. Dependent lung is on a more favorable part of the compliance curve

D. The lower lung receives less ventilation and more perfusion than the upper lung

18. In an open pneumothorax, the major effect of mediastinal shift is to

A. Decrease the contribution of dependent lung to the tidal volume

B. Move air to and fro between the dependent and the nondependent lung

C. Decrease the perfusion to the dependent lung

D. Compress the big veins and decrease cardiac preload

19. Factors known to inhibit hypoxic pulmonary vasoconstriction (HPV) and thus worsen

the alveolar–arterial oxygen gradient include all of the following, except

A. Hypocapnia

B. Nitroglycerin

C. Hypercapnia

D. Pulmonary infection

20. A 64-year-old female is undergoing a left video-assisted thoracoscopy for a

suspicious pulmonary nodule. Immediately after positioning the patient laterally,

which of the following alarms indicates a malposition of the double-lumen tube

(DLT)?

A. High CO2 alarm

B. Low O2 alarm

C. Low tidal volume alarm

D. Unable to drive bellows alarm

21. A bronchial blocker is useful in all of the following clinical situations, except

A. Patient to be left intubated post operatively

B. Anatomical abnormality precluding the placement of a double-lumen tube

(DLT)

C. Tamponading bronchial bleeding in adult patients

D. To attain better collapse of the nondependent lung

22. Which of the following statements about lung resection surgery is false?

A. Mortality rate for pneumonectomy is 5% to 7%

B. Mortality rate for lobectomy is 2% to 3%

C. Mortality is higher for left-sided pneumonectomy

D. Most postoperative deaths result from cardiac issues

23. Regarding lung resection surgery, which of the following statements is false?

A. Perioperative arrhythmias are common

B. Supraventricular tachycardias (SVTs) are thought to result from surgical

manipulation or distension of the right atrium

C. Incidence of arrhythmia decreases with age due to the ageing of cardiac

conduction system

D. Postoperative hypoxemia and acidosis due to atelectasis and shallow breathing

are common

24. Which of the following has the least effect on hypoxic pulmonary vasoconstriction

(HPV)?

A. Nitrous oxide

B. Desflurane end tidal 5.5%

C. Sevoflurane end tidal 2.5%

D. Isoflurane end tidal 1.5%

25. Which of the following statements is not true regarding “lower lung syndrome”?

A. It is caused by excessive fluid administration in a lateral decubitus position

B. It increases intrapulmonary shunting

C. It is gravity-dependent transudation of fluid into the dependent lung

D. It is due to volutrauma caused during one-lung ventilation

26. The first step recommended to improve oxygenation if a patient is exhibiting drop in

oxygen saturation during one-lung ventilation is

A. Apply continuous positive-airway pressure (CPAP) to the collapsed lung

B. Apply positive end–expiratory pressure (PEEP) to the dependent lung

C. Periodic inflation of the collapsed lung

D. Continuous inflation of oxygen into collapsed lung

27. During apneic oxygenation,

A. Adequate oxygenation can be maintained only for short periods of time

B. Arterial PCO2

rises 3 to 4 mm Hg in the first minute

C. Arterial PCO2

rises 1 to 2 mm Hg each subsequent minute after the first minute

D. Progressive respiratory acidosis limits the use of this technique to 10 to 20

minutes in most patients

28. A 68-year-old male patient with a lung nodule underwent a right upper lobectomy.

On postoperative day 4, the patient develops a sudden large air leak from the chest

tube associated with increasing pneumothorax and partial lung collapse. The most

likely cause is

A. Bronchopleural fistula on the right from necrosis of suture line

B. Bronchopleural fistula on the right from inadequate surgical closure of the

bronchial stump

C. Atelectasis causing shifting of the mediastinum to the left

D. A normal finding

29. An 80-year-old female underwent a left lower lobectomy. In the ICU on

postoperative day 2, she develops hemoptysis. The vital signs are stable, but on the

chest X-ray a homogenous density is seen in the left lower lung area. After

subsequent bronchoscopy, the left upper lobar orifice is closed. The most likely

diagnosis is

A. Acute herniation of the heart into the left lower lobe area

B. It is a normal finding and the homogenous opacity is due to accumulation of

fluid in the left lower lobe area

C. Torsion of the left upper lobe as the left upper lobe expanded to occupy the left

hemithorax

D. Reexpansion edema of the left upper lobe

30. A 45-year-old recent immigrant from Vietnam is admitted to the emergency

department with massive hemoptysis (>600 mL in the last 24 hours). You are called

to evaluate the patient for a possible bronchial artery embolization or a rigid

bronchoscopy. In your discussion with the patient, which of the following statements

is not appropriate about his clinical condition?

A. Operative mortality exceeds 20%

B. It can be done as a semi-elective procedure, and there is no need to do it

emergently

C. The most common cause of death is asphyxia secondary to blood in the airway

D. Medical management has a lower mortality rate than operative management

31. An 81-year-old chronic smoker, with a history of 60 pack year smoking, is admitted

with progressive dyspnea and a huge right-sided pulmonary cyst. The cyst is

compressing her remaining right lung, and she is brought to the OR for an emergency

pulmonary cystectomy. Which of the following is right regarding anesthetic

management of this patient?

A. The greatest risk of rupture of the cavity is during preoxygenation just prior to

induction

B. These cavities allow to and fro movement of air and have a very low chance to

progressively enlarge

C. Maintenance of spontaneous ventilation is desirable until a double-lumen tube

(DLT) is in place

D. Assisted ventilation is not necessary immediately after induction and can be

harmful

32. A 66-year-old patient with a history of severe tracheal stenosis is presenting for a

tracheal resection. The most unlikely clinical finding is

A. Progressive dyspnea

B. Wheezing evident on exertion

C. Dyspnea worse on sitting up and leaning forward

D. Patient may have a history of blunt/penetrating tracheal trauma

33. In the anesthetic management of the above patient, which of the following statements

is correct?

A. Flow–volume loops aid the clinician in evaluating the severity of the lesion

B. Right radial artery blood pressure monitoring is preferred over the left side for

lower tracheal resection

C. Slow-inhalation induction is not advisable and a rapid-sequence induction

should be used

D. Early extubation is not advisable at the end of the procedure for risk of

rupturing the suture lines

34. Complications associated with mediastinoscopy include all the following, except

A. Vagally mediated reflex bradycardia

B. Cerebral ischemia

C. Pneumothorax

D. Thoracic duct injury

35. Anesthetic considerations for bronchoalveolar lavage include all the following,

except

A. It is performed for patients who make excess quantities of surfactant and fail to

clear it

B. It is performed under general anesthesia with lung isolation

C. It is usually performed in the supine position

D. It involves positioning the patient in a lateral position to aid active suctioning of

the lavage fluid

36. Considerations for lung transplantation include all the following, except

A. Cor pulmonale does not necessarily require combined heart–lung transplantation

B. Patients with diminished left-ventricular function can be transplanted as long as

they have normal right-ventricular function

C. Patients with Eisenmenger syndrome require combined heart–lung

transplantation

D. Organ selection is based on size and ABO compatibility

37. After a double-lung transplantation

A. Loss of lymphatic drainage predisposes to pulmonary edema

B. Respiratory pattern changes to a slow deep respiration

C. Cough reflex is abolished above the carina

D. Hypoxic pulmonary vasoconstriction is abolished

38. Anesthetic considerations for esophageal surgery include

A. Very low risk of pulmonary aspiration

B. Mandatory pulmonary artery catheter monitoring

C. Diaphragmatic retractors interfering with cardiac function

D. Always performed with a double-lumen tube (DLT)

39. Lung-volume-reduction surgery (LVRS)

A. Has been demonstrated to have very good efficacy by the National Emphysema

Treatment Trial (NETT)

B. Necessitates limiting of peak inspiratory pressure to 30 cm H2O following

intubation

C. A prolonged inspiratory time is recommended for facilitating exposure of the

surgical segments

D. Patients have a better outcome if kept intubated at the end of the surgery

40. Which of the following flow–volume loops will be expected in a child with variable

extrathoracic obstruction?

Figure 12-2.

41. A 12-year-old boy with suspected lymphoma presents to you for a lymph node

biopsy. When you go to visit the patient, you notice that he has venous engorgement

and edema of the head, neck, and arms. He refuses to lie down, and is tachycardiac

and tachypneic. The preferred management for this boy would be

A. Safest thing will be to secure the airway immediately by using rapid-sequence

induction

B. Preferably biopsy the lymph node under local anesthesia so that the patient can

be sent for radiotherapy immediately after a tissue diagnosis

C. Empiric treatment with steroids and surgery under general anesthesia only after

the airway compromise is alleviated

D. Get a chest X-ray and rule out mediastinal compression prior to any active

management

CHAPTER 12 ANSWERS

1. D. Asthma is a type of reactive airway disease characterized by hyperresponsive

airways, reversible expiratory airflow obstruction, and chronic inflammation. Sudden

bronchospasm in response to external/internal stimuli and response to bronchodilators

like β2

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