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The patient interview and record can be divided into sections with subjective and

objective data as well as an assessment and plan (including expected outcomes).

Components of subjective and objective data are the medical history, medication

history, and social history. In some situations, histories can be supplemented by the

generation of flowchart diagrams to monitor changes in specific variables with time.

These charts and documentation systems may be incorporated into the EHR, PIS, or a

similar electronic platform.

Medical History

A medical history is essential to the provision of MTMS. It can be as extensive as the

medical records that are maintained in an institution or physician’s office, or it can

be a simple patient profile that is maintained in a community pharmacy. The purpose

of the medical history is to identify significant past medical conditions or procedures;

identify, characterize, and assess current acute and chronic medical conditions and

symptoms; and gather all relevant health information that could influence drug

selection or dosing (e.g., function of major organs such as the gastrointestinal tract,

liver, and kidney; height and weight, including recent changes in either; age and sex;

pregnancy and lactation status; and special nutritional needs). Not all interviews

require the interviewer to ask for this much general information; however, in a datapoor environment, more information is required directly from the patient. A more

focused interview may be appropriate in settings in which the information required is

available electronically or is specific to a single disease state.

CASE 1-1

QUESTION 1: P.J., a 45-year-old woman of normal height and weight, states that she has diabetes. What

questions might the practitioner ask P.J. to determine whether type 1 or type 2 diabetes should be documented

in her medical history?

Patients usually can enumerate their medical problems in a general way, but the

practitioner often will have to probe more specifically to refine the diagnosis and

assess the severity of the condition. Diabetes mellitus is used to illustrate the types of

questions that can be used to gather important health information and assess drug

therapy. The following questions should generate information that will help to

determine whether P.J. has type 1 or type 2 diabetes.

How old were you when you were told you had diabetes?

Do any of your relatives have diabetes? What do you know of their diabetes?

Do you remember your symptoms? Please describe them to me.

What medications have you used to treat your diabetes?

When questions such as these are combined with knowledge of the

pathophysiology of diabetes, appreciation of the typical presenting signs and

symptoms of the disease, and understanding of the drugs generally used to treat both

forms of diabetes, meaningful MTM can be provided.

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Medication History

In the community pharmacy setting, patients generally present themselves in one of

four ways: (a) with a self-diagnosed condition for which nonprescription drug

therapy is sought, (b) with a newly diagnosed condition for which a drug has been

prescribed, (c) with a chronic condition that requires a refill of a previously

prescribed drug or the initiation of a new drug, or (d) upon referral from their health

plan or provider, or self-referral for focused medication therapy review (MTR).

In the first and second situations, the practitioner must confirm the diagnosis by

using disease-specific questions as illustrated in Question 1. In the third situation, the

practitioner uses the same type of questioning as in the first two situations; however,

this time the practitioner needs to evaluate whether the desired therapeutic outcomes

have been achieved. The practitioner must evaluate the information gleaned during

follow-up visits in the context of the history and incorporate it into his or her

assessment and medication action plan (MAP). In the fourth situation, in which

patients require a focused MTR, the medication and medical history information are

equally important. Without the medical history, it is not possible to evaluate whether

the drug therapy is appropriate, and without an accurate medication history, it is not

possible to determine whether the patient has reached the desired goals of therapy for

her condition.

The goal of the medication history is to obtain and assess the following

information: the specific prescription and nonprescription drugs that the patient is

taking (such as OTC medications, botanicals, dietary supplements, recreational

drugs, alcohol, tobacco, and home remedies); the intended purpose or indications for

each of these medications; how it is taken (e.g., route, ingestion in relation to meals),

how much, and how often these medications are used; how long these agents have

been taken or used (start and stop dates); whether the patient believes that any of

these agents are providing therapeutic benefit; whether the patient is experiencing or

has experienced any adverse effects that could be caused by each of these agents

(idiosyncratic reactions, toxic effects, adverse effects); whether the patient has

stopped taking any of the medications for any reason; and allergic reactions or history

of hypersensitivity or other severe reactions to drugs. This information should be as

specific as possible, including a description of the reaction, the treatment, and the

date of its occurrence.

A successful medication reconciliation process consists of a standardized

systematic approach, with the initial step in this process involving the collection of

the best medication history possible from every patient that enters any point in the

health care system. Although pharmacists are uniquely qualified and have

demonstrated increased accuracy in acquiring the medication history,

18 medication

reconciliation requires a multidisciplinary effort in which all available resources are

integrated into each step of the process when appropriate.

19 Shared accountability by

using key members of the health care team such as nurses, pharmacy technicians,

pharmacists, and prescribers is essential in this process. Once an accurate

medication history is obtained, this information is used to ensure that as the patient

moves through the health care system, any deviation from prescribed regimen is

deliberate and based on acute changes in the patient’s condition. If an observed

discrepancy is the result of an intended therapeutic decision by the prescribing

clinician, appropriate documentation with either the reason for or intention to change,

hold, or discontinue the medication should be completed in a manner that is clear to

all members of the health care team. Unintentional variances in the medication lists

should be considered as potential medication errors pending clarification from the

prescribing clinician.

Medication errors most commonly occur during transitions of care. It is essential

to conduct medication reconciliation when a patient is admitted to or discharged from

a health care facility.

20,21 A crucial final step in the reconciliation process, and a vital

piece of MTMS, occurs at discharge to avoid therapeutic duplication, drug

interactions, and omissions of medications that may have been discontinued or placed

on hold during hospitalization. On departure from a health care facility, a complete

list of the patient’s medications must be communicated to the patient and the next

provider of service regardless of the setting. This process allows for informed

prescribing decisions and creates a safer environment for patients by improving the

accuracy of medication administration throughout the continuum of care.

Perhaps the most important aspect of the medication history is to ensure that no

assumptions related to medication use go unverified with the patient. The provider

should ask questions related to how the current medication therapy is actually taken

by the patient. The interviewer should then compare the use of medications as

defined by the patient to the prescription information on the prescription bottle or in

the PIS/EHR. This information may identify discrepancies or misunderstandings

between the prescriber and the patient. The patient may not have adequate health

literacy, and the interpretation of the medication instructions printed on the bottle or

described by a health professional may not be understandable to a patient. The

review of the medication history is an ideal time to identify and clarify such

misunderstandings.

CASE 1-1, QUESTION 2: P.J. has indicated that she is injecting insulin to treat her diabetes. What questions

might be asked to evaluate P.J.’s use of and response to insulin?

The following types of questions, when asked of P.J., should provide the

practitioner with information on P.J.’s understanding about the use of and response to

insulin.

DRUG IDENTIFICATION AND USE

What type of insulin do you use?

How many units of insulin do you use?

When do you inject your insulin?

Where do you inject your insulin?

Please show me how you usually prepare your insulin for injection. (This allows the

patient to demonstrate a skill.)

What, if anything, keeps you from taking your insulin as prescribed?

ASSESSMENT OF THERAPEUTIC RESPONSE

How do you know your insulin is working?

What blood glucose levels are you aiming for?

What foods or meals do you find affect your blood sugar most?

How often and when do you test your blood glucose level?

Do you have any blood glucose readings that you could share with me?

Please show me how you test your blood glucose.

What is your understanding of the hemoglobin A1c blood test?

When was the last time you had this test done?

What were the results of the last hemoglobin A1c

test?

ASSESSMENT OF ADVERSE EFFECTS

Do you ever experience reactions from low blood glucose?

What symptoms warn you of such a reaction?

When do these typically occur during the day?

How often do they occur?

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What circumstances seem to make them occur more frequently?

What do you do when you have low blood glucose?

The patient’s responses to these questions on drug use, therapeutic response, and

adverse effects will allow a quick assessment of the patient’s knowledge of

insulin and whether she is using it in a way that is likely to result in blood glucose

concentrations that are neither too high nor too low. The responses to these

questions should also provide the practitioner with insight about the extent to

which the patient has been involved in establishing and monitoring therapeutic

outcomes. Based on this information, the practitioner can begin to formulate the

patient’s therapeutic plan.

Social History

The social history is used to determine the patient’s occupation and lifestyle;

important family relationships or other support systems; any particular circumstances

(e.g., a disability) or stresses in her life that could influence the MAP; and attitudes,

values, and feelings about health, illness, and treatments.

CASE 1-1, QUESTION 3: A patient’s occupation, lifestyle, insurance status, ability to pay, and attitudes often

can determine the success or failure of drug therapy. Therefore, P.J.’s prescription drug coverage, nutritional

history, her level of activity or exercise in a typical day or week, the family dynamics, and any particular

stresses that may affect glucose control need to be documented and assessed. What questions might be asked

of P.J. to gain this information?

WORK

Describe your typical workday and a typical weekend day.

INSURANCE/COST

What type of prescription drug coverage do you have? How much do you pay for

your insulin and diabetic supplies? How often do you go without your insulin or

supplies because of cost?

EXERCISE

Describe your exercise habits. How often, how long, and when during the day do

you exercise? Describe how you change your meals or insulin when you exercise.

DIET

How many times per day do you usually eat? Describe your usual meal times.

What do you usually eat for each of your main meals and snacks?

Are you able to eat at the same time each day?

What do you do if a meal is delayed or missed?

Who cooks the meals at home? Does this person understand foods to prepare for

someone with diabetes?

How often do you eat meals in a restaurant?

How do you order meals in a restaurant to maintain a proper diet for your diabetes?

(Note: This is asked to patients who frequently dine in restaurants.)

SUPPORT SYSTEMS

Who else lives with you? What do they know about diabetes? How do they respond

to the fact that you have diabetes? How do they help you with your diabetes

management? Does it ever strain your relationship? What are the issues that seem

to be most troublesome? (Note: These questions apply equally to the workplace

or school setting. Often, the biggest barrier to multiple daily injections is refusal

of the patient to inject insulin while at work or school.)

ATTITUDE

How do you feel about having diabetes?

What worries or bothers you most about having diabetes? (Note: Participate in the

patient’s care. This approach is likely to enhance the patient–provider

relationship, which should translate into improved care.)

APPROACH TO AND ASSESSMENT OF PATIENT

THERAPY

The provider–patient encounter will vary based on the location and type of services

provided and access to necessary information. However, the general approach to the

patient encounter should follow the problem-oriented medical record (POMR).

Organizing information according to medical problems (e.g., diseases) helps to break

down a complex situation (e.g., a patient with multiple medical problems requiring

multiple drugs) into its individual parts.

1,2 The medical community has long used a

POMR or SOAP note to record information in the medical record or chart by using a

standardized format (Table 1-4). Each medical problem is identified, listed

sequentially, and assigned a number. Subjective data and objective data in support of

each problem are delineated, an assessment is made, and a plan of action identified.

The first letter of the four key words (subjective, objective, assessment, and plan)

serves as the basis for the SOAP acronym.

Table 1-4

Elements of the Problem-Oriented Medical Record

Problem name: Each “problem” is listed separately and given an identifying number. Problems may be a patient

complaint (e.g., headache), a laboratory abnormality (e.g., hypokalemia), or a specific disease name if prior

diagnosis is known. When monitoring previously described drug therapy, more than one drug-related problem

may be considered (e.g., lack of adherence, an adverse drug reaction or drug interaction, or inappropriate dose).

Under each problem name, the following information is identified:

Subjective Information that explains the reason for the encounter. Information that the patient reports

concerning symptoms, previous treatments, medications used, and adverse effects encountered.

These are considered nonreproducible data because the information is based on the patient’s

interpretation and recall of past events.

Objective Information from physical examination, laboratory test results, diagnostic tests, pill counts, and

pharmacy patient profile information. Objective data are measurable and reproducible.

Assessment A brief but complete description of the problem, including a conclusion or diagnosis that is

supported logically by the above subjective and objective data. The assessment should not include a

problem or diagnosis that is not defined above.

Plan A detailed description of recommended or intended further workup (laboratory tests, radiology,

consultation), treatment (e.g., continued observation, physiotherapy, diet, medications, surgery),

patient education (self-care, goals of therapy, medication use, and monitoring), monitoring, and

follow-up relative to the above assessment.

Sometimes referred to as the SOAP (subjective, objective, assessment, plan) note.

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