Moncada, S. & Vane , J. R. (1977). The discovery of prostacyclin - a fresh insight into arachidon ic acid metabolism. In Biochemica/ Aspects of Prostag/andins and Thromb oxanes, ed.

Kharasch, N. & Fried, J., pp 155-177. NewYork, San Francisco, London: Academic Press.

Mon cada, S. & Vane , J. R. (1978). Unstable metabolites of arachidonic acid and their role in

haemostasis and thrombosis. Brit. med. Bu/1.. 34, 129-135.

Moncada, S. & Vane, J. R. (1979a). Mode of action of aspirin-like drugs, In Advances in

Interna/ Medicine, Vol. 24, ed. Stollerman, G . H., pp 1-22. Chicago, London: Year Book

Medical Publishers, Inc.

Moncada , S. & Vane , J. R. (l979b). The role of prostacyclin in vascular tissue. Fed. Proc., 38,

62-66.

Moriau, M., Masure, R., Hurlet, A., Debeys , c.,Chalant, c., Poulot, R., Jaumain, P., ServayeKestens , Y., Ra vaux, A., Louis, A. & Goenen, M. (1977). Haemostasis disorders in open

heart surgery with extracorporeal circulation. Vox Sanguinis, 32,41-51.

Mullane, K. M., Dusting, G . J., Salmon, J. A., Moncada, S. & Vane , J. R. (1979a). Biotransformation and cardiovascular effects of arachidonic acid in the dog. Eur.J. Pharmac., 54,

217-2 28.

PROSTACYCLl N, PHARMACOLOGY ANDCLl NICAL POTENTIAL 31

Mullane, K. M., Moncada, S. & Vane ,J. R. (l979b). Prostacyclin release induced by bradykinin

may contribute to the anti-hypertensive action of angiotensin con verting enzyme inhibitors. In 4th International Prostaglandin Congress p 84. Washington, D.C. , May, 1979.

Mustard,J. F. & Packham, M. A. (1975). Platelets, thrombosis and drugs. Drugs, 9, 19-76.

Needleman, P. (1976). The synthesis and function ofprostaglandins in the heart . Fed. Proc., 35,

2376--2381.

Needleman, P., Bronson, S. D., Wyche, A., Sivakoff, M. & Nicolaou, K. (1978). Cardiac and

renal prostaglandin h . J. c1in.lnvest., 61, 839-849.

Needleman, P., Bryan, B., Wyche, A., Bronson , S. D., Eakins, K., Ferrendelli, J. A. & Minkes ,

M. (1977). Thromboxane synthetase inhibitors as pharmacological tools; differential

biochemical and biological effects on platelet suspensions. Prostaglandins, 14, 897-907.

Needleman, P., Moncada, S., Bunting, S., Vane , J. R., Hamberg, M. & Samuel sson , 8.(1976).

Ident ificat ion of an enzyme in platelet microsomes which generates thromboxane Al from

prostaglandin endoperoxides. Nature, 261.558-560.

Needleman, P., Wyche , A & Raz, A. (1979). Platelet and blood vessel arachidonate metabolism

and interactions. J. clin.Tnvest., 63, 345-349.

Nijkamp, F. P., Moncada, S., White, H. L. & Vane, J R. (1977). Diversion of prostaglandin

endoperoxide metabolism by selective inhibition ofthromboxane Al biosynthesis in lung,

spleen or platelets. Eur. J. Pharmac., 44. 179-187.

Nugteren, D. H. & Hazelhof, E. (1973). Isolation and properties of intermediates in prostaglandin biosynthesis. Biochim. Biophys. Acta., 326,448-461.

O'Brien,J. R. (1968). Effects ofsalicylates on human platelets. Lancet, 1, 779-783.

O'Grady, J. & Moncada, S. (1978). Aspirin : A paradoxical effect on bleeding time. Lancet, 2, 780.

O'Grady, J., Warrington, S., Moti , M. J., Bunting, S., Flower, R. J., Fowle, A.S.E., Higgs, E. A.

& Moncada, S. (1979). Effects of intravenous prostacyclin infusions in healthy

volunteers - some preliminary observations. In Prostacyclin ed. Vane , J. R. & Bergstrom ,

S., pp 409-417. New York: Raven Press.

Owen , T. L., Ehrhart, I. c., Weidner, W. J., Scott , J. B. & Hadd y, F. J. (1975). Effects of

indomethacin on local blood flow regulation in can ine heart and kidney. Proc. Soc. exp.

Biol. Med., 149,871-876.

Pace-Asciak, C. R., Carrara, M. c.,Rangaraj, G . & Nicolaou, K.G. (1978). Enhanced formation

of PGh, a potent hypotensive substance, by aortic rings and homogenates of the

spontaneously hypertensive rat. Prostaglandins, 15, 1005-1012.

Patterson, R. H. & Kessler, J. (1969). A filter for micro-emboli in cardiopulmonary bypass.

Circulation, 40, 160.

Piper, P.J. & Vane , J. R. (1969). Release ofadditional factors in anaphylaxis and its antagonism

by anti-inflarnmatory drugs. Nature, 223,29-35.

Pomerantz, K., Sintetos, A. & Ramwell, P. (1978). The effect of prostacyclin on the human

umbilical artery. Prostaglandins, 15, 1035-1044.

Quick, A. J. (1966). Salicylates and bleeding: the aspirin tolerance test. Am. J. med. Sei., 252,

265-269.

Rajah, S. M., Penny, S. & Kester , R. (1978). Aspirin and bleeding time . Lancet, 2, 1104.

Raz, A., Isakson, P. C; Minkes , M. S. & Needleman, P. (1977). Characterisation of a novel

metabolic pathway of arachidonate in coronary arte ries which generates a potent endogenous coronary vasodilator. J. biol. Chem., 252, 1123-1126.

Remuzzi, G., Cavenaghi, A. E., Mecca , G., Donati, M. B. & Oe Gaetano, G . (1977). Prostacyclin (PGh) and bleeding time in uremic patients. Thromb. Res., 11,919-920.

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