Adrenaline 100micrograms/20ml (1 in 200,000) solution for injection

vials | 5 vial P £8.85 DT = £8.85

Lidocaine with cetrimide 27-Apr-2018

The properties listed below are those particular to the

combination only. For the properties of the components

please consider, lidocaine hydrochloride p. 103.

l INDICATIONS AND DOSE

Anaesthesia and disinfection in dental practice

▶ TO MUCOUS MEMBRANES USING OROMUCOSAL SPRAY

▶ Adult: 10–20 mg, no more than 30 mg should be

applied to the same quadrant of the buccal cavity—

consult product literature, dose expressed as lidocaine

Anaesthesia in dental practice

▶ TO MUCOUS MEMBRANES USING DENTAL GEL

▶ Adult: Apply 100–500 mg, use cotton pellet for

application to dried mucosa, dose expressed as weight

of gel

DOSE EQUIVALENCE AND CONVERSION

▶ 1 metered dose of Xylonor ® spray is equivalent to 10 mg

of lidocaine.

▶ 2 millimetres of Xylonor ® gel is approximately

equivalent to 100 mg of gel (approximately equivalent

to 5 mg of lidocaine).

l CAUTIONS Sepsis (risk of rapid systemic absorption). traumatised mucosa (risk of rapid systemic absorption)

l INTERACTIONS → Appendix 1: antiarrhythmics

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Oromucosal gel

▶ Xylonor (Septodont Ltd)

Cetrimide 1.5 mg per 1 gram, Lidocaine 50 mg per 1 gram Xylonor

5% gel sugar-free | 15 gram P £4.00

Spray

▶ Xylonor (Septodont Ltd)

Cetrimide 100 microgram per 1 gram, Lidocaine 10 mg per

1 gram Xylonor 10% spray sugar-free | 36 gram P £20.15

Lidocaine with phenylephrine

The properties listed below are those particular to the

combination only. For the properties of the components

please consider, lidocaine hydrochloride p. 103,

phenylephrine hydrochloride p. 189.

l INDICATIONS AND DOSE

Anaesthesia before nasal surgery, endoscopy,

laryngoscopy, or removal of foreign bodies from the nose

▶ BY INTRANASAL ADMINISTRATION

▶ Adult: Up to 8 sprays

l INTERACTIONS → Appendix 1: antiarrhythmics . sympathomimetics, vasoconstrictor

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Spray

▶ Lidocaine with phenylephrine (Non-proprietary)

Phenylephrine hydrochloride 5 mg per 1 ml, Lidocaine

hydrochloride 50 mg per 1 ml Lidocaine 5% / Phenylephrine 0.5%

nasal spray | 2.5 ml P £12.90 DT = £12.90

Lidocaine with prilocaine 25-Apr-2019

The properties listed below are those particular to the

combination only. For the properties of the components

please consider, lidocaine hydrochloride p. 103, prilocaine

hydrochloride p. 1356.

l INDICATIONS AND DOSE

Anaesthesia before minor skin procedures including

venepuncture

▶ TO THE SKIN

▶ Child 1–2 months: Apply up to 1 g for maximum 1 hour

before procedure, to be applied under occlusive

dressing, shorter application time of 15–30 minutes is

recommended for children with atopic dermatitis

(30 minutes before removal of mollusca); maximum

1 dose per day

▶ Child 3–11 months: Apply up to 2 g for maximum 1 hour

before procedure, to be applied under occlusive

dressing, shorter application time of 15–30 minutes is

recommended for children with atopic dermatitis

(30 minutes before removal of mollusca); maximum

2 doses per day

▶ Child 1–11 years: Apply 1–5 hours before procedure, a

thick layer should be applied under occlusive dressing,

shorter application time of 15–30 minutes is

recommended for children with atopic dermatitis

(30 minutes before removal of mollusca); maximum

2 doses per day

▶ Child 12–17 years: Apply 1–5 hours before procedure

(2–5 hours before procedures on large areas e.g. split

skin grafting), a thick layer should be applied under

occlusive dressing, shorter application time of

15–30 minutes is recommended for children with

atopic dermatitis (30 minutes before removal of

mollusca)

▶ Adult: Apply 1–5 hours before procedure (2–5 hours

before procedures on large areas e.g. split skin

grafting), a thick layer should be applied under

occlusive dressing

Anaesthesia on genital skin before injection of local

anaesthetics

▶ TO THE SKIN

▶ Adult: Apply under occlusive dressing for 15 minutes

(males) or 60 minutes (females) before procedure

Anaesthesia before surgical treatment of lesions on

genital mucosa

▶ TO THE SKIN

▶ Adult: Apply up to 10 g, to be applied 5–10 minutes

before procedure

Anaesthesia before cervical curettage

▶ TO THE SKIN

▶ Adult: Apply 10 g in lateral vaginal fornices for

10 minutes

Anaesthesia before mechanical cleansing or debridement

of leg ulcer

▶ TO THE SKIN

▶ Adult: Apply up to 10 g for 30–60 minutes, to be

applied under occlusive dressing

FORTACIN ®

Primary premature ejaculation

▶ TO THE SKIN

▶ Adult: 3 sprays every 4 hours as required, to be applied

to cover the glans penis (excess spray should be

removed after 5 minutes and before intercourse);

maximum 9 sprays per day

DOSE EQUIVALENCE AND CONVERSION

▶ For Fortacin ®: Each dose of 3 sprays is equivalent to

lidocaine 22.5 mg and prilocaine 7.5 mg.

1354 Local anaesthesia BNF 78

Anaesthesia

15