They do not benefit from anti-infective treatment.

The management of primary herpetic gingivostomatitis is

a soft diet, adequate fluid intake, and analgesics as required,

including local use of benzydamine hydrochloride p. 1215.

The use of chlorhexidine mouthwash p. 1211 will control

plaque accumulation if toothbrushing is painful and will also

help to control secondary infection in general.

In the case of severe herpetic stomatitis, a systemic

antiviral such as aciclovir p. 633 is required. Valaciclovir

p. 636 and famciclovir p. 635 are suitable alternatives for oral

lesions associated with herpes zoster. Aciclovir and

valaciclovir are also used for the prevention of frequently

recurring herpes simplex lesions of the mouth, particularly

when implicated in the initiation of erythema multiforme.

BNF 78 Oropharyngeal viral infections 1219

Ear, nose and oropharynx

12

Chapter 13

Skin

CONTENTS

1 Dry and scaling skin disorders page 1221

2 Infections of the skin 1228

2.1 Bacterial skin infections 1230

2.2 Fungal skin infections 1232

2.3 Parasitic skin infections 1236

2.4 Viral skin infections 1238

3 Inflammatory skin conditions 1238

3.1 Eczema and psoriasis 1238

4 Perspiration 1264

4.1 Hyperhidrosis 1264

5 Pruritus 1265

6 Rosacea and acne 1266

6.1 Acne 1267

6.2 Rosacea page 1273

7 Scalp and hair conditions 1274

7.1 Alopecia 1275

7.2 Hirsutism 1275

8 Skin cleansers, antiseptics and desloughing

agents

1276

8.1 Minor cuts and abrasions 1279

9 Skin disfigurement 1280

10 Sun protection and photodamage 1280

11 Superficial soft-tissue injuries and superficial

thrombophlebitis

1283

12 Warts and calluses 1283

Skin conditions, management

Vehicles

The British Association of Dermatologists list of preferred

unlicensed dermatological preparations (specials) is

available at www.bad.org.uk/specials.

Both vehicle and active ingredients are important in the

treatment of skin conditions; the vehicle alone may have

more than a mere placebo effect. The vehicle affects the

degree of hydration of the skin, has a mild anti-inflammatory

effect, and aids the penetration of active drug.

Applications are usually viscous solutions, emulsions, or

suspensions for application to the skin (including the scalp)

or nails.

Collodions are painted on the skin and allowed to dry to

leave a flexible film over the site of application.

Creams are emulsions of oil and water and are generally

well absorbed into the skin. They may contain an

antimicrobial preservative unless the active ingredient or

basis is intrinsically bactericidal and fungicidal. Generally,

creams are cosmetically more acceptable than ointments

because they are less greasy and easier to apply.

Gels consist of active ingredients in suitable hydrophilic or

hydrophobic bases; they generally have a high water

content. Gels are particularly suitable for application to the

face and scalp.

Lotions have a cooling effect and may be preferred to

ointments or creams for application over a hairy area.

Lotions in alcoholic basis can sting if used on broken skin.

Shake lotions (such as calamine lotion) contain insoluble

powders which leave a deposit on the skin surface.

Ointments are greasy preparations which are normally

anhydrous and insoluble in water, and are more occlusive

than creams. They are particularly suitable for chronic, dry

lesions. The most commonly used ointment bases consist of

soft paraffin or a combination of soft, liquid, and hard

paraffin. Some ointment bases have both hydrophilic and

lipophilic properties; they may have occlusive properties on

the skin surface, encourage hydration, and also be miscible

with water; they often have a mild anti-inflammatory effect.

Water-soluble ointments contain macrogols which are freely

soluble in water and are therefore readily washed off; they

have a limited but useful role where ready removal is

desirable.

Pastes are stiff preparations containing a high proportion of

finely powdered solids such as zinc oxide and starch

suspended in an ointment. They are used for circumscribed

lesions such as those which occur in lichen simplex, chronic

eczema, or psoriasis. They are less occlusive than ointments

and can be used to protect inflamed, lichenified, or

excoriated skin.

Dusting powders are used only rarely. They reduce

friction between opposing skin surfaces. Dusting powders

should not be applied to moist areas because they can cake

and abrade the skin. Talc is a lubricant but it does not absorb

moisture; it can cause respiratory irritation. Starch is less

lubricant but absorbs water.

Dilution

The BP directs that creams and ointments should not

normally be diluted but that should dilution be necessary

care should be taken, in particular, to prevent microbial

contamination. The appropriate diluent should be used and

heating should be avoided during mixing; excessive dilution

may affect the stability of some creams. Diluted creams

should normally be used within 2 weeks of preparation.

Suitable quantities for prescribing

Suitable quantities of dermatological

preparations to be prescribed for specific areas

of the body

Area of body Creams and Ointments Lotions

Face 15–30 g 100 ml

Both hands 25–50 g 200 ml

Scalp 50–100 g 200 ml

Both arms or both legs 100–200 g 200 ml

Trunk 400 g 500 ml

Groins and genitalia 15–25 g 100 ml

These amounts are usually suitable for an adult for twice daily

application for 1 week. The recommendations do not apply to

corticosteroid preparations. For suitable quantities of

corticosteroid preparations, see relevant table.

1220 Skin BNF 78

Skin

13

Excipients and sensitisation

Excipients in topical products rarely cause problems. If a

patch test indicates allergy to an excipient, products

containing the substance should be avoided. The following

excipients in topical preparations are associated, rarely, with

sensitisation; the presence of these excipients is indicated in

the entries for topical products.

. Beeswax

. Benzyl alcohol

. Butylated hydroxyanisole

. Butylated hydroxytoluene

. Cetostearyl alcohol (including cetyl and stearyl alcohol)

. Chlorocresol

. Edetic acid (EDTA)

. Ethylenediamine

. Fragrances

. Hydroxybenzoates (parabens)

. Imidurea

. Isopropyl palmitate

. N-(3-Chloroallyl)hexaminium chloride (quaternium 15)

. Polysorbates

. Propylene glycol

. Sodium metabisulfite

. Sorbic acid

. Wool fat and related substances including lanolin (purified

versions of wool fat have reduced the problem)

1 Dry and scaling skin

disorders

Emollient and barrier preparations

Borderline substances

The preparations marked ‘ACBS’ are regarded as drugs when

prescribed in accordance with the advice of the Advisory

Committee on Borderline Substances for the clinical

conditions listed. Prescriptions issued in accordance with

this advice and endorsed ‘ACBS’ will normally not be

investigated.

Emollients

Emollients soothe, smooth and hydrate the skin and are

indicated for all dry or scaling disorders. Their effects are

short lived and they should be applied frequently even after

improvement occurs. They are useful in dry and eczematous

disorders, and to a lesser extent in psoriasis. The choice of an

appropriate emollient will depend on the severity of the

condition, patient preference, and the site of application.

Some ingredients rarely cause sensitisation and this should

be suspected if an eczematous reaction occurs. The use of

aqueous cream as a leave-on emollient may increase the risk

of skin reactions, particularly in eczema.

Preparations such as aqueous cream and emulsifying

ointment can be used as soap substitutes for hand washing

and in the bath; the preparation is rubbed on the skin before

rinsing off completely. The addition of a bath oil may also be

helpful.

Urea is occasionally used with other topical agents such as

corticosteroids to enhance penetration of the skin.

Emollient bath and shower preparations

Emollient bath additives should be added to bath water;

hydration can be improved by soaking in the bath for

10–20 minutes. Some bath emollients can be applied to wet

skin undiluted and rinsed off. In dry skin conditions soap

should be avoided.

The quantities of bath additives recommended for adults

are suitable for an adult-size bath. Proportionately less

should be used for a child-size bath or a washbasin;

recommended bath additive quantities for children reflect

this.

MHRA/CHM advice (updated December 2018): Emollients:

new information about risk of severe and fatal burns with

paraffin-containing and paraffin-free emollients

Emollients are an important and effective treatment for

chronic dry skin disorders and people should continue to use

these products. However, healthcare professionals must

ensure that patients and their carers understand the fire risk

associated with the build-up of residue on clothing and

bedding and can take action to minimise the risk. There is a

fire risk with all paraffin-containing emollients, regardless of

paraffin concentration, and it cannot be excluded with

paraffin-free emollients. A similar risk may apply to products

that are applied to the skin over large body areas, or in large

volumes for repeated use for more than a few days.

Healthcare professionals should advise patients not to

smoke or go near naked flames because clothing, bedding,

dressings, and other fabrics that have been in contact with

an emollient or emollient-treated skin can rapidly ignite.

Washing these materials at high temperature may reduce

emollient build-up but not totally remove it.

Barrier preparations

Barrier preparations often contain water-repellent

substances such as dimeticone p. 1236 or other silicones.

They are used on the skin around stomas, bedsores, and

pressure areas in the elderly where the skin is intact. Where

the skin has broken down, barrier preparations have a

limited role in protecting adjacent skin. Barrier preparations

are not a substitute for adequate nursing care.

Nappy rash

The first line of treatment is to ensure that nappies are

changed frequently and that tightly fitting water-proof pants

are avoided. The rash may clear when left exposed to the air

and a barrier preparation, applied with each nappy change,

can be helpful. A mild corticosteroid such as hydrocortisone

0.5% or 1% p. 1247 can be used if inflammation is causing

discomfort, but it should be avoided in neonates. The barrier

preparation should be applied after the corticosteroid

preparation to prevent further damage. Preparations

containing hydrocortisone should be applied for no more

than a week; the hydrocortisone should be discontinued as

soon as the inflammation subsides. The occlusive effect of

nappies and waterproof pants may increase absorption of

corticosteroids. If the rash is associated with candidal

infection, a topical antifungal such as clotrimazole cream

p. 1232 can be used. Topical antibacterial preparations can

be used if bacterial infection is present; treatment with an

oral antibacterial may occasionally be required in severe or

recurrent infection. Hydrocortisone may be used in

combination with antimicrobial preparations if there is

considerable inflammation, erosion, and infection.

DERMATOLOGICAL DRUGS › BARRIER

PREPARATIONS

Barrier creams and ointments

l INDICATIONS AND DOSE

For use as a barrier preparation

▶ TO THE SKIN

▶ Child: (consult product literature)

▶ Adult: (consult product literature)

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Ointment

EXCIPIENTS: May contain Woolfat and related substances (including

lanolin)

BNF 78 Dry and scaling skin disorders 1221

Skin

13

▶ Barrier creams and ointments (Non-proprietary)

Cetostearyl alcohol 20 mg per 1 gram, Zinc oxide 75 mg per

1 gram, Beeswax white 100 mg per 1 gram, Arachis oil 305 mg

per 1 gram, Castor oil 500 mg per 1 gram Zinc and Castor oil

ointment | 500 gram G £5.14–£5.19 DT = £5.19

Zinc and Castor oil cream | 100 gram G £1.46

▶ Metanium (Thornton & Ross Ltd)

Titanium salicylate 30 mg per 1 gram, Titanium peroxide 50 mg

per 1 gram, Titanium dioxide 200 mg per 1 gram Metanium Nappy

Rash ointment | 30 gram G £2.24 DT = £2.24

Spray

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and

stearyl alcohol), hydroxybenzoates (parabens), woolfat and related

substances (including lanolin)

▶ Sprilon (J M Loveridge Ltd)

Dimeticone 10.4 mg per 1 gram, Zinc oxide 125 mg per

1 gram Sprilon aerosol spray | 115 gram G £8.90 DT = £8.90

Cream

EXCIPIENTS: May contain Beeswax, butylated hydroxyanisole, butylated

hydroxytoluene, cetostearyl alcohol (including cetyl and stearyl alcohol),

chlorocresol, fragrances, hydroxybenzoates (parabens), propylene glycol,

woolfat and related substances (including lanolin)

▶ Conotrane (LEO Pharma)

Benzalkonium chloride 1 mg per 1 gram, Dimeticone 220 mg per

1 gram Conotrane cream | 100 gram G £0.88 DT = £0.88 |

500 gram G £3.51

▶ Drapolene (Supra Enterprises Ltd)

Benzalkonium chloride 100 microgram per 1 gram, Cetrimide

2 mg per 1 gram Drapolene cream | 100 gram G £1.76 | 200 gram G £2.86 | 350 gram G £4.28

▶ Siopel (Derma UK Ltd)

Cetrimide 3 mg per 1 gram, Dimeticone 1000 100 mg per

1 gram Siopel cream | 50 gram G £4.65

▶ Sudocrem (Teva UK Ltd)

Benzyl cinnamate 1.5 mg per 1 gram, Benzyl alcohol 3.9 mg per

1 gram, Benzyl benzoate 10.1 mg per 1 gram, Wool fat hydrous

40 mg per 1 gram, Zinc oxide 152.5 mg per 1 gram Sudocrem

antiseptic healing cream | 30 gram G £1.45 | 60 gram G £1.45 | 125 gram G £2.15 | 250 gram G £3.67 |

400 gram G £5.25

DERMATOLOGICAL DRUGS › EMOLLIENTS

Emollient bath and shower products,

antimicrobial-containing 31-Aug-2016

l INDICATIONS AND DOSE

DERMOL ® 200 SHOWER EMOLLIENT

Dry and pruritic skin conditions including eczema and

dermatitis

▶ TO THE SKIN

▶ Child: To be applied to the skin or used as a soap

substitute

▶ Adult: To be applied to the skin or used as a soap

substitute

DERMOL ® 600 BATH EMOLLIENT

Dry and pruritic skin conditions including eczema and

dermatitis

▶ TO THE SKIN

▶ Child 1–23 months: 5–15 mL/bath, not to be used

undiluted

▶ Child 2–17 years: 15–30 mL/bath, not to be used

undiluted

▶ Adult: Up to 30 mL/bath, not to be used undiluted

DERMOL ® WASH EMULSION

Dry and pruritic skin conditions including eczema and

dermatitis

▶ TO THE SKIN

▶ Child: To be applied to the skin or used as a soap

substitute

▶ Adult: To be applied to the skin or used as a soap

substitute

EMULSIDERM ®

Dry skin conditions including eczema and ichthyosis

▶ TO THE SKIN

▶ Child 1–23 months: 5–10 mL/bath, alternatively, to be

rubbed into dry skin until absorbed

▶ Child 2–17 years: 7–30 mL/bath, alternatively, to be

rubbed into dry skin until absorbed

▶ Adult: 7–30 mL/bath, alternatively, to be rubbed into

dry skin until absorbed

OILATUM ® PLUS

Topical treatment of eczema, including eczema at risk

from infection

▶ TO THE SKIN

▶ Child 6–11 months: 1 mL/bath, not to be used undiluted

▶ Child 1–17 years: 1–2 capfuls/bath, not to be used

undiluted

▶ Adult: 1–2 capfuls/bath, not to be used undiluted

IMPORTANT SAFETY INFORMATION

These preparations make skin and surfaces slippery—

particular care is needed when bathing.

MHRA/CHM ADVICE (UPDATED DECEMBER 2018): EMOLLIENTS:

NEW INFORMATION ABOUT RISK OF SEVERE AND FATAL BURNS

WITH PARAFFIN-CONTAINING AND PARAFFIN-FREE EMOLLIENTS

See Emollient and barrier preparations p. 1221.

l DIRECTIONS FOR ADMINISTRATION Emollient bath

additives should be added to bath water; hydration can be

improved by soaking in the bath for 10–20 minutes. Some

bath emollients can be applied to wet skin undiluted and

rinsed off. Emollient preparations contained in tubs

should be removed with a clean spoon or spatula to reduce

bacterial contamination of the emollient. Emollients

should be applied in the direction of hair growth to reduce

the risk of folliculitis.

l PRESCRIBING AND DISPENSING INFORMATION

Preparations containing an antibacterial should be

avoided unless infection is present or is a frequent

complication.

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Bath additive

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Acetylated lanolin alcohols, isopropyl

palmitate, polysorbates

▶ Dermol 600 (Dermal Laboratories Ltd)

Benzalkonium chloride 5 mg per 1 gram, Isopropyl myristate

250 mg per 1 gram, Liquid paraffin 250 mg per 1 gram Dermol

600 bath emollient | 600 ml p £7.55

▶ Emulsiderm (Dermal Laboratories Ltd)

Benzalkonium chloride 5 mg per 1 gram, Isopropyl myristate

250 mg per 1 gram, Liquid paraffin 250 mg per

1 gram Emulsiderm emollient | 300 ml p £3.85 | 1000 ml p

£12.00

▶ Oilatum Plus (GlaxoSmithKline Consumer Healthcare)

Triclosan 20 mg per 1 gram, Benzalkonium chloride 60 mg per

1 gram, Liquid paraffin light 525 mg per 1 gram Oilatum Plus bath

additive | 500 ml G £7.22

Liquid

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and

stearyl alcohol)

▶ Dermol 200 (Dermal Laboratories Ltd)

Benzalkonium chloride 1 mg per 1 gram, Chlorhexidine

hydrochloride 1 mg per 1 gram, Isopropyl myristate 25 mg per

1 gram, Liquid paraffin 25 mg per 1 gram Dermol 200 shower

emollient | 200 ml p £3.55

▶ Dermol Wash (Dermal Laboratories Ltd)

Benzalkonium chloride 1 mg per 1 gram, Chlorhexidine

hydrochloride 1 mg per 1 gram, Isopropyl myristate 25 mg per

1 gram, Liquid paraffin 25 mg per 1 gram Dermol Wash cutaneous

emulsion | 200 ml p £3.55

1222 Dry and scaling skin disorders BNF 78

Skin

13

Emollient bath and shower products,

paraffin-containing 15-Aug-2016

l INDICATIONS AND DOSE

AQUAMAX ® WASH

Dry skin conditions

▶ TO THE SKIN

▶ Child: To be applied to wet or dry skin and rinse

▶ Adult: To be applied to wet or dry skin and rinse

CETRABEN ® BATH

Dry skin conditions, including eczema

▶ TO THE SKIN

▶ Child 1 month–11 years: 0.5–1 capful/bath, alternatively,

to be applied to wet skin and rinse

▶ Child 12–17 years: 1–2 capfuls/bath, alternatively, to be

applied to wet skin and rinse

▶ Adult: 1–2 capfuls/bath, alternatively, to be applied to

wet skin and rinse

DERMALO ®

Dermatitis | Dry skin conditions, including ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: 5–10 mL/bath, alternatively, to

be applied to wet skin and rinse

▶ Child 12–17 years: 15–20 mL/bath, alternatively, to be

applied to wet skin and rinse

▶ Adult: 15–20 mL/bath, alternatively, to be applied to

wet skin and rinse

Pruritus of the elderly

▶ TO THE SKIN

▶ Elderly: 15–20 mL/bath, alternatively, to be applied to

wet skin and rinse

DOUBLEBASE ® EMOLLIENT BATH ADDITIVE

Dry skin conditions including dermatitis and ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: 5–10 mL/bath

▶ Child 12–17 years: 15–20 mL/bath

▶ Adult: 15–20 mL/bath

Pruritus of the elderly

▶ TO THE SKIN

▶ Elderly: 15–20 mL/bath

DOUBLEBASE ® EMOLLIENT SHOWER GEL

Dry, chapped, or itchy skin conditions

▶ TO THE SKIN

▶ Child: To be applied to wet or dry skin and rinse, or

apply to dry skin after showering

▶ Adult: To be applied to wet or dry skin and rinse, or

apply to dry skin after showering

E45 ® BATH OIL

Endogenous and exogenous eczema, xeroderma, and

ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: 5–10 mL/bath, alternatively, to

be applied to wet skin and rinse

▶ Child 12–17 years: 15 mL/bath, alternatively, to be

applied to wet skin and rinse

▶ Adult: 15 mL/bath, alternatively, to be applied to wet

skin and rinse

Pruritus of the elderly associated with dry skin

▶ TO THE SKIN

▶ Elderly: 15 mL/bath, alternatively, to be applied to wet

skin and rinse

E45 ® WASH CREAM

Endogenous and exogenous eczema, xeroderma, and

ichthyosis

▶ TO THE SKIN

▶ Child: To be used as a soap substitute

▶ Adult: To be used as a soap substitute

Pruritus of the elderly associated with dry skin

▶ TO THE SKIN

▶ Elderly: To be used as a soap substitute

HYDROMOL ® BATH AND SHOWER EMOLLIENT

Dry skin conditions | Eczema | Ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: 0.5–2 capfuls/bath, alternatively

apply to wet skin and rinse

▶ Child 12–17 years: 1–3 capfuls/bath, alternatively apply

to wet skin and rinse

▶ Adult: 1–3 capfuls/bath, alternatively apply to wet skin

and rinse

Pruritus of the elderly

▶ TO THE SKIN

▶ Elderly: 1–3 capfuls/bath, alternatively apply to wet

skin and rinse

LPL 63.4 ®

Dry skin conditions

▶ TO THE SKIN

▶ Child 1 month–11 years: 0.5–2 capfuls/bath,

alternatively, to be applied to wet skin and rinse

▶ Child 12–17 years: 1–3 capfuls/bath, alternatively, to be

applied to wet skin and rinse

▶ Adult: 1–3 capfuls/bath, alternatively, to be applied to

wet skin and rinse

OILATUM ® EMOLLIENT BATH ADDITIVE

Dry skin conditions including dermatitis and ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: Apply 0.5–2 capfuls/bath,

alternatively, to be applied to wet skin and rinse

▶ Child 12–17 years: 1–3 capfuls/bath, alternatively, to be

applied to wet skin and rinse

▶ Adult: 1–3 capfuls/bath, alternatively, to be applied to

wet skin and rinse

Pruritus of the elderly

▶ TO THE SKIN

▶ Elderly: 1–3 capfuls/bath, alternatively, to be applied

to wet skin and rinse

OILATUM ® JUNIOR BATH ADDITIVE

Dry skin conditions including dermatitis and ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: 0.5–2 capfuls/bath,

alternatively, apply to wet skin and rinse

▶ Child 12–17 years: 1–3 capfuls/bath, alternatively, apply

to wet skin and rinse

▶ Adult: 1–3 capfuls/bath, alternatively, apply to wet skin

and rinse

Pruritus of the elderly

▶ TO THE SKIN

▶ Elderly: 1–3 capfuls/bath, alternatively, apply to wet

skin and rinse

QV ® BATH OIL

Dry skin conditions including eczema, psoriasis,

ichthyosis, and pruritus

▶ TO THE SKIN

▶ Child 1–11 months: 5 mL/bath, alternatively, to be

applied to wet skin and rinse

▶ Child 1–17 years: 10 mL/bath, alternatively, to be applied

to wet skin and rinse

▶ Adult: 10 mL/bath, alternatively, to be applied to wet

skin and rinse

QV ® GENTLE WASH

Dry skin conditions including eczema, psoriasis,

ichthyosis, and pruritus

▶ TO THE SKIN

▶ Child: To be used as a soap substitute

▶ Adult: To be used as a soap substitute continued→

BNF 78 Dry and scaling skin disorders 1223

Skin

13

ZEROLATUM ®

Dry skin conditions | Dermatitis | Ichthyosis

▶ TO THE SKIN

▶ Child 1 month–11 years: 5–10 mL/bath

▶ Child 12–17 years: 15–20 mL/bath

▶ Adult: 15–20 mL/bath

Pruritus of the elderly

▶ TO THE SKIN

▶ Elderly: 15–20 mL/bath

IMPORTANT SAFETY INFORMATION

These preparations make the skin and surfaces

slippery—particular care is needed when bathing.

MHRA/CHM ADVICE (UPDATED DECEMBER 2018): EMOLLIENTS:

NEW INFORMATION ABOUT RISK OF SEVERE AND FATAL BURNS

WITH PARAFFIN-CONTAINING AND PARAFFIN-FREE EMOLLIENTS

See Emollient and barrier preparations p. 1221.

l DIRECTIONS FOR ADMINISTRATION Emollient bath

additives should be added to bath water; hydration can be

improved by soaking in the bath for 10–20 minutes. Some

bath emollients can be applied to wet skin undiluted and

rinsed off. Emollient preparations contained in tubs

should be removed with a clean spoon or spatula to reduce

bacterial contamination of the emollient. Emollients

should be applied in the direction of hair growth to reduce

the risk of folliculitis.

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Bath additive

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Acetylated lanolin alcohols, cetostearyl

alcohol (including cetyl and stearyl alcohol), fragrances, isopropyl

palmitate

▶ Cetraben (Genus Pharmaceuticals Ltd)

Liquid paraffin light 828 mg per 1 gram Cetraben emollient 82.8%

bath additive | 500 ml G £5.75 DT = £5.75

▶ Dermalo (Dermal Laboratories Ltd)

Acetylated wool alcohols 50 mg per 1 gram, Liquid paraffin

650 mg per 1 gram Dermalo bath emollient | 500 ml G £3.44

▶ Doublebase (Dermal Laboratories Ltd)

Liquid paraffin 650 mg per 1 gram Doublebase emollient bath

additive | 500 ml G £5.45 DT = £5.45

▶ E45 emollient bath (Forum Health Products Ltd)

E45 emollient bath oil | 250 ml(ACBS) £3.30 | 500 ml(ACBS) £5.29

▶ Hydromol (Alliance Pharmaceuticals Ltd)

Isopropyl myristate 130 mg per 1 ml, Liquid paraffin light 378 mg

per 1 ml Hydromol Bath & Shower emollient | 350 ml £3.91 | 500 ml

£4.46 | 1000 ml £8.87

▶ LPL (Huxley Europe Ltd)

Liquid paraffin light 634 mg per 1 ml LPL 63.4 bath additive and

emollient | 500 ml £3.10 DT = £5.27

▶ Oilatum (GlaxoSmithKline Consumer Healthcare)

Liquid paraffin light 634 mg per 1 ml Oilatum Bath Formula |

150 ml G £2.95 DT = £2.95 | 300 ml G £5.02 DT = £5.02

▶ Oilatum junior (GlaxoSmithKline Consumer Healthcare)

Liquid paraffin light 634 mg per 1 ml Oilatum Junior bath additive

| 150 ml G £2.95 DT = £2.95 | 250 ml G £4.44 DT = £2.75 | 300 ml G £5.02 DT = £5.02 | 600 ml G £6.67 DT = £6.67

▶ QV (Crawford Healthcare Ltd)

Liquid paraffin light 850.9 mg per 1 gram QV 85.09% bath oil | 250 ml £2.93 | 500 ml £4.79

▶ Zerolatum (Thornton & Ross Ltd)

Acetylated wool alcohols 50 mg per 1 gram, Liquid paraffin

650 mg per 1 gram Zerolatum Emollient bath additive | 500 ml

£4.79

Gel

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and

stearyl alcohol)

▶ Doublebase (Dermal Laboratories Ltd)

Isopropyl myristate 150 mg per 1 gram, Liquid paraffin 150 mg

per 1 gram Doublebase emollient shower gel | 200 gram p £5.21

Wash

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and

stearyl alcohol), hydroxybenzoates, polysorbates

▶ Aquamax (Intrapharm Laboratories Ltd)

Aquamax wash | 250 gram £2.99

▶ E45 emollient wash (Forum Health Products Ltd)

E45 emollient wash cream | 250 ml(ACBS) £3.30

▶ QV Gentle (Crawford Healthcare Ltd)

QV Gentle wash | 250 ml £3.19 | 500 ml £5.32

Emollient bath and shower products,

soya-bean oil-containing

l INDICATIONS AND DOSE

BALNEUM ® BATH OIL

Dry skin conditions including those associated with

dermatitis and eczema

▶ TO THE SKIN

▶ Child 1–23 months: 5–15 mL/bath, not to be used

undiluted

▶ Child 2–17 years: 20–60 mL/bath, not to be used

undiluted

▶ Adult: 20–60 mL/bath, not to be used undiluted

BALNEUM ® PLUS BATH OIL

Dry skin conditions including those associated with

dermatitis and eczema where pruritus also experienced

▶ TO THE SKIN

▶ Child 1–23 months: 5 mL/bath, alternatively, to be

applied to wet skin and rinse

▶ Child 2–17 years: 10–20 mL/bath, alternatively, to be

applied to wet skin and rinse

▶ Adult: 20 mL/bath, alternatively, to be applied to wet

skin and rinse

ZERONEUM ®

Dry skin conditions, including eczema

▶ TO THE SKIN

▶ Child 1 month–11 years: 5 mL/bath

▶ Child 12–17 years: 20 mL/bath

▶ Adult: 20 mL/bath

IMPORTANT SAFETY INFORMATION

These preparations make skin and surfaces slippery—

particular care is needed when bathing.

MHRA/CHM ADVICE (UPDATED DECEMBER 2018): EMOLLIENTS:

NEW INFORMATION ABOUT RISK OF SEVERE AND FATAL BURNS

WITH PARAFFIN-CONTAINING AND PARAFFIN-FREE EMOLLIENTS

See Emollient and barrier preparations p. 1221.

l DIRECTIONS FOR ADMINISTRATION Emollient bath

additives should be added to bath water; hydration can be

improved by soaking in the bath for 10–20 minutes. Some

bath emollients can be applied to wet skin undiluted and

rinsed off. Emollient preparations contained in tubs

should be removed with a clean spoon or spatula to reduce

bacterial contamination of the emollient. Emollients

should be applied in the direction of hair growth to reduce

the risk of folliculitis.

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Bath additive

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Butylated hydroxytoluene, fragrances,

propylene glycol

▶ Balneum (Almirall Ltd)

Lauromacrogols 150 mg per 1 gram, Soya oil 829.5 mg per

1 gram Balneum Plus bath oil | 500 ml G £6.66 DT = £6.66

Soya oil 847.5 mg per 1 gram Balneum 84.75% bath oil | 500 ml G £5.38 DT = £5.38 | 1000 ml G £10.39 DT = £10.39

1224 Dry and scaling skin disorders BNF 78

Skin

13

▶ Zeroneum (Thornton & Ross Ltd)

Soya oil 833.5 mg per 1 gram Zeroneum 83.35% bath additive | 500 ml £4.48

Emollient bath and shower products,

tar-containing 17-Aug-2016

l INDICATIONS AND DOSE

POLYTAR EMOLLIENT ®

Psoriasis, eczema, atopic and pruritic dermatoses

▶ TO THE SKIN

▶ Adult: 2–4 capfuls/bath, add 15–30 mL to an adult-size

bath; soak for 20 minutes

PSORIDERM ® EMULSION

Psoriasis

▶ TO THE SKIN

▶ Adult: Up to 30 mL/bath, use 30mL in adult-size bath,

soak for 5 minutes

IMPORTANT SAFETY INFORMATION

These preparations make skin and surfaces slippery—

particular care is needed when bathing.

MHRA/CHM ADVICE (UPDATED DECEMBER 2018): EMOLLIENTS:

NEW INFORMATION ABOUT RISK OF SEVERE AND FATAL BURNS

WITH PARAFFIN-CONTAINING AND PARAFFIN-FREE EMOLLIENTS

See Emollient and barrier preparations p. 1221.

l DIRECTIONS FOR ADMINISTRATION Emollient bath

additives should be added to bath water; hydration can be

improved by soaking in the bath for 10–20 minutes. Some

bath emollients can be applied to wet skin undiluted and

rinsed off. Emollient preparations contained in tubs

should be removed with a clean spoon or spatula to reduce

bacterial contamination of the emollient. Emollients

should be applied in the direction of hair growth to reduce

the risk of folliculitis.

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Bath additive

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Isopropyl palmitate, polysorbates

▶ Psoriderm (Dermal Laboratories Ltd)

Coal tar distilled 400 mg per 1 ml Psoriderm Emulsion 40% bath

additive | 200 ml p £2.74 DT = £2.74

Emollient creams and ointments,

antimicrobial-containing 17-Aug-2016

l INDICATIONS AND DOSE

Dry and pruritic skin conditions including eczema and

dermatitis

▶ TO THE SKIN

▶ Child: To be applied to the skin or used as a soap

substitute

▶ Adult: To be applied to the skin or used as a soap

substitute

IMPORTANT SAFETY INFORMATION

These preparations make skin and surfaces slippery—

particular care is needed when bathing.

MHRA/CHM ADVICE (UPDATED DECEMBER 2018): EMOLLIENTS:

NEW INFORMATION ABOUT RISK OF SEVERE AND FATAL BURNS

WITH PARAFFIN-CONTAINING AND PARAFFIN-FREE EMOLLIENTS

See Emollient and barrier preparations p. 1221.

l DIRECTIONS FOR ADMINISTRATION Emollients should be

applied immediately after washing or bathing to maximise

the effect of skin hydration. Emollient preparations

contained in tubs should be removed with a clean spoon or

spatula to reduce bacterial contamination of the emollient.

Emollients should be applied in the direction of hair

growth to reduce the risk of folliculitis.

l PRESCRIBING AND DISPENSING INFORMATION

Preparations containing an antibacterial should be

avoided unless infection is present or is a frequent

complication.

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Cream

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and

stearyl alcohol)

▶ Dermol (Dermal Laboratories Ltd)

Benzalkonium chloride 1 mg per 1 gram, Chlorhexidine

hydrochloride 1 mg per 1 gram, Isopropyl myristate 100 mg per

1 gram, Liquid paraffin 100 mg per 1 gram Dermol cream | 100 gram p £2.86 | 500 gram p £6.63

Liquid

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and

stearyl alcohol)

▶ Dermol 500 (Dermal Laboratories Ltd)

Benzalkonium chloride 1 mg per 1 gram, Chlorhexidine

hydrochloride 1 mg per 1 gram, Isopropyl myristate 25 mg per

1 gram, Liquid paraffin 25 mg per 1 gram Dermol 500 lotion | 500 ml p £6.04

Emollient creams and ointments,

colloidal oatmeal-containing 15-Jan-2019

l INDICATIONS AND DOSE

Endogenous and exogenous eczema | Xeroderma |

Ichthyosis

▶ TO THE SKIN

▶ Child: (consult product literature)

▶ Adult: (consult product literature)

Senile pruritus (pruritus of the elderly) associated with

dry skin

▶ TO THE SKIN

▶ Elderly: (consult product literature)

IMPORTANT SAFETY INFORMATION

MHRA/CHM ADVICE (UPDATED DECEMBER 2018): EMOLLIENTS:

NEW INFORMATION ABOUT RISK OF SEVERE AND FATAL BURNS

WITH PARAFFIN-CONTAINING AND PARAFFIN-FREE EMOLLIENTS

See Emollient and barrier preparations p. 1221.

l DIRECTIONS FOR ADMINISTRATION Emollients should be

applied immediately after washing or bathing to maximise

the effect of skin hydration. Emollient preparations

contained in tubs should be removed with a clean spoon or

spatula to reduce bacterial contamination of the emollient.

Emollients should be applied in the direction of hair

growth to reduce the risk of folliculitis.

l MEDICINAL FORMS There can be variation in the licensing of

different medicines containing the same drug.

Lotion/Cream

CAUTIONARY AND ADVISORY LABELS 15

EXCIPIENTS: May contain Benzyl alcohol, cetostearyl alcohol (including

cetyl and stearyl alcohol), isopropyl palmitate

▶ Aveeno (Johnson & Johnson Ltd)

Aveeno lotion | 500 ml(ACBS) £6.66

Aveeno cream | 100 ml(ACBS) £3.97 | 300 ml(ACBS) £6.80 | 500 ml

(ACBS) £6.47

BNF 78 Dry and scaling skin disorders 1225

Skin

13

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